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90809 PIP4P1

90809

PIP4P1

phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1

研究结论

Date Results Publications
2018-11-10 11:26:00 Results suggest that TMEM55B contributes to assembly of the V-ATPase complex in lipid rafts of the lysosomal membrane and to subsequent activation of mTORC1. 29644770
2018-09-15 10:25:00 these data suggest that the TFEB/TMEM55B/JIP4 pathway coordinates lysosome movement in response to a variety of stress conditions. 29146937
2014-10-25 11:43:00 Expression array profiling was performed on lymphoblastoid cell lines from statin clinical trial participants showed sterol-regulated expression of TMEM55B. Knockdown promoted LDL receptor decay and decreased its cholesterol uptake. 25035345
2010-01-21 00:00:00 Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase (type I 4-phosphatase), an enzyme that dephosphorylates phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P(2)), forming PtdIns-5-P in vitro, can increase the cellular levels of PtdIns-5-P. 17940011
2010-01-21 00:00:00 identification and characterization of two previously undescribed human enzymes, PtdIns-4,5-P(2) 4-phosphatase type I and type II 16365287

名称对应

Type IDs
Synonymous C14orf9, TMEM55B
Gene
UniProtKB-ID: PP4P1_HUMAN
UniprotKB: Q86T03
UniParc: UPI000000CC01, UPI00001B3DC9, UPI00001B3DC8
EMBL: BX161490, AK314021, BC002867, BX248025, BC020947, CH471078, AL137727
Ensembl: ENSG00000165782
KO: hsa:90809
Nucleutide sequences
EMBL-CDS: CAB70896.1, AAH20947.1, AAH02867.2, CAD61939.1, CAD62347.1, BAG36732.1, EAW66461.1
Ensembl_TRS: ENST00000398020, ENST00000250489
Protein sequencees
Ensembl_PRO: ENSP00000250489, ENSP00000381102
RefSeq: NP_001094284.1, XP_024305508.1, XP_024305507.1, NP_653169.2
Others
UniRef100: UniRef100_Q86T03
UniRef90: UniRef90_Q86T03
UniRef50: UniRef50_Q86T03
UniGene: Hs.7001
CCDS: CCDS9551.1, CCDS41911.1

全选

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