| Type | Description |
|---|---|
| Definition | claudin 10 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:01:00 | Immune-related key gene CLDN10 correlates with lymph node metastasis but predicts favorable prognosis in papillary thyroid carcinoma. | 32045884 |
| 2020-03-28 12:07:00 | Study describes a novel claudinopathy that is based on mutations in the CLDN10 gene and characterized by an impaired function of mainly claudin-10b. Patients show a salt-losing nephropathy without hypercalciuria, and the severity of clinical manifestations may depend on site and type of mutation. [review] | 31671507 |
| 2018-12-29 12:03:00 | The CLDN10 polymorphism of rs1325774 was significantly associated with an increased risk of breast cancer. After adjusting for age, the association remained statically significant. Furthermore, harbouring G allele in rs1325774 position was significantly associated with increased risk of breast cancer. However, no significant association among rs7333503, rs3751334, and breast cancer. | 30544377 |
| 2017-08-05 10:11:00 | These renal-derived features recapitulate several phenotypic aspects detected in mice with kidney specific loss of both claudin-10 isoforms. Our study adds to the spectrum of phenotypes caused by tight junction proteins and demonstrates a pivotal role for claudin-10b in maintaining paracellular Na+ permeability for sweat production and kidney function. | 28686597 |
| 2016-09-03 10:55:00 | localization of Cldn3, Cldn7 and Cldn10 proteins in the different compartments of murine endometrium up to day 8.5 of pregnancy (dpc) as well as in human endometrium and first trimester decidua | 26340953 |
| Type | IDs |
|---|---|
| Synonymous | CPETRL3, HELIX, OSP-L, OSPL |
| Gene |
UniProtKB-ID:
CLD10_HUMAN
UniprotKB:
P78369
UniParc:
UPI0000127AB3,
UPI0001A4717D,
UPI0000037786
EMBL:
AL627382,
AL139376,
CH471085,
BC010920,
U89916,
AK315737,
CR456845,
AK055855,
AL357061
Ensembl:
ENSG00000134873
KO:
hsa:9071
|
| Nucleutide sequences |
EMBL-CDS:
EAX08955.1,
AAH10920.1,
BAB71030.1,
BAG38092.1,
AAC79506.1,
CAG33126.1
Ensembl_TRS:
ENST00000299339,
ENST00000376873
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366069,
ENSP00000299339
RefSeq:
XP_016876332.1,
NP_001153572.1,
NP_008915.1,
XP_016876333.1,
XP_011519436.1,
XP_024305200.1,
NP_878268.1
|
| Others |
UniRef100:
UniRef100_P78369
UniRef90:
UniRef90_P78369
UniRef50:
UniRef50_P78369
UniGene:
Hs.534377
CCDS:
CCDS9475.1,
CCDS9476.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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