| Type | Description |
|---|---|
| Definition | ASH2 like, histone lysine methyltransferase complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:16:00 | Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization. | 32071397 |
| 2020-06-20 12:40:00 | Our findings suggest that ASH2L participates in the promotion of endometrial cancer progression, if not totally at least partially, via upregulation of PAX2 transcription. | 32279431 |
| 2020-05-16 13:12:00 | Circ-ASH2L served as a miRNA sponge for miR-34a and promoted tumor progression in vivo. Finally, we analyzed circ-ASH2L expression in clinical tissues and found that high circ-ASH2L expression was correlated with lymphatic invasion and TNM stage and was an independent risk factor for pancreatic patient survival. | 31718694 |
| 2020-04-18 11:43:00 | unliganded glucocorticoid receptor and ASH2L may act as key regulatory players of BCL- XL upregulation in acute myeloid leukemia cells. | 31870784 |
| 2019-02-16 10:13:00 | berrant histone methylation of IFN-gamma associating H3K4me3 and H3K27me3 caused by over-binding of Ash2L and Jmjd3 might be involved in immune dysfunction and vascular damage in Kawasaki disease in the acute phase. | 29036979 |
| Type | IDs |
|---|---|
| Synonymous | ASH2, ASH2L1, ASH2L2, Bre2 |
| Gene |
UniProtKB-ID:
ASH2L_HUMAN,
B4DPT1_HUMAN,
F5H8F7_HUMAN
UniprotKB:
Q9UBL3,
B4DPT1,
F5H8F7
UniParc:
UPI0000169F6C,
UPI0001D3C95C,
UPI0000038D65,
UPI000013CCC6,
UPI00017A774C
EMBL:
AC084024,
BC015936,
AB022785,
AP006545,
AK291938,
AB020982,
AK298483,
AF056717,
AF056718,
CH471080
Ensembl:
ENSG00000129691
KO:
hsa:9070
|
| Nucleutide sequences |
EMBL-CDS:
BAA35127.1,
AAC13563.1,
AAC13564.1,
EAW63340.1,
BAA74520.1,
EAW63337.1,
AAH15936.1,
EAW63336.1,
BAF84627.1,
BAG60693.1
Ensembl_TRS:
ENST00000343823,
ENST00000428278,
ENST00000521652,
ENST00000545394
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000430259,
ENSP00000395310,
ENSP00000340896,
ENSP00000443606
RefSeq:
XP_005273740.1,
NP_001098684.1,
XP_005273739.1,
XP_006716476.1,
NP_001248761.1,
XP_006716475.1,
NP_004665.2,
NP_001269201.1
|
| Others |
UniRef100:
UniRef100_Q9UBL3,
UniRef100_B4DPT1,
UniRef100_F5H8F7
UniRef90:
UniRef90_A0A3Q0GHT7,
UniRef90_Q9UBL3
UniRef50:
UniRef50_Q9UBL3,
UniRef50_A0A3Q0GHT7
UniGene:
Hs.521530
CCDS:
CCDS59100.1,
CCDS6101.1,
CCDS47840.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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