| Type | Description |
|---|---|
| Definition | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 14:59:00 | In all patients, exome and Sanger sequencing identified homozygous or compound heterozygous PAPSS2 variants, including c.809G>A, common to white European patients. | 31313512 |
| 2020-06-06 12:01:00 | Depletion of PAPSS2 in MCF7 and MDA-MB-231 cells results in reduced cell migration, while overexpression of PAPSS2 promotes cell migration. | 29955124 |
| 2019-01-26 11:52:00 | Energy-dependent scoring of docking solutions identified the interaction as specific for the PAPSS2 and SULT2A1 isoforms | 29743239 |
| 2017-07-29 10:38:00 | In an Amish population, using expression profiling of genes within regions identified by a meta-analysis GWAS of survival to age 90, we localized PAPSS2 as a candidate gene for extended life span. These results provide novel evidence for genetic loci implicated in longevity and incorporate gene expression results from a unique population to locate positional candidates. | 26896383 |
| 2017-05-20 14:54:00 | Silencing of SULT1A1 and PAPSS2 led to a significant decrease in aristolactam-DNA levels in both cell lines following exposure to AA-I, indicating the critical role for sulfonation in the activation of AA-I in vivo Since HK-2 cells proved relatively resistant to knockdown with siRNAs | 27207664 |
| Type | IDs |
|---|---|
| Synonymous | ATPSK2, BCYM4, SK2 |
| Gene |
UniProtKB-ID:
PAPS2_HUMAN,
Q5TB52_HUMAN
UniprotKB:
O95340,
Q5TB52
UniParc:
UPI000002B182,
UPI0000132103
EMBL:
AF160503,
AF173365,
AF160504,
AF313907,
AF160506,
AF091242,
GQ891452,
AF160507,
BC009894,
AF160508,
AF074331,
AK312556,
AF160505,
AF160509,
CH471066,
AF150754
Ensembl:
ENSG00000198682
KO:
hsa:9060
|
| Nucleutide sequences |
EMBL-CDS:
AAF12761.1,
AAF20366.2,
AAF40307.2,
AAH09894.1,
AAK00296.1,
AAD38423.1,
AAC64583.1,
ADO22314.1,
EAW50182.1,
BAG35453.1
Gene_ORFName:
hCG_23331
Ensembl_TRS:
ENST00000361175,
ENST00000456849
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406157,
ENSP00000354436
RefSeq:
NP_004661.2,
NP_001015880.1
|
| Others |
UniRef100:
UniRef100_O95340
UniRef90:
UniRef90_O95340
UniRef50:
UniRef50_O95340
UniGene:
Hs.524491
CCDS:
CCDS7385.1,
CCDS44453.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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