| Type | Description |
|---|---|
| Definition | solute carrier family 7 member 7 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 11:42:00 | The three mutations studied of y+LAT1 transporter result in a defective arginine transport both in ex vivo (monocytes) and in vitro (CHO transfected cells) models, likely caused by the retention of the mutated proteins in the cytosol | 30832686 |
| 2019-04-27 10:32:00 | SLC7A7 gene detection showed three pathogenic mutations in these children, namely c.1387delG(p.V463CfsX56), c.1215G>A(p.W405X) and homozygous c.625+1G>A | 31014432 |
| 2019-04-13 12:18:00 | this study shows that downregulation of SLC7A7 triggers an inflammatory phenotype in human macrophages and airway epithelial cells | 29616026 |
| 2018-09-22 10:37:00 | SLC7A7 overexpression decreased the apoptosis rate, increased the proportion of cells in the G1 phase, decreased the proportion of G2 cells, and significantly increased cell migration and invasion and increased intracellular arginine would activate mTOR, and induce apoptosis in SLC7A7 knockdown Jurkat cells. | 30025393 |
| 2018-09-01 11:15:00 | Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 and SLC38A5 showed marked differences between controls and intrauterine growth restriction/pre-eclampsia and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of pre-eclempsia. | 29499643 |
| Type | IDs |
|---|---|
| Synonymous | LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1 |
| Gene |
UniProtKB-ID:
YLAT1_HUMAN,
A0A0S2Z502_HUMAN
UniprotKB:
Q9UM01,
A0A0S2Z502
UniParc:
UPI000000CC04
EMBL:
AB020532,
AB011263,
AK314351,
CH471078,
KU178460,
BC003062,
BC010107,
AJ130718,
AB031537,
BX161519,
BX248291,
Y18474,
AF092032
Ensembl:
ENSG00000155465
KO:
hsa:9056
|
| Nucleutide sequences |
EMBL-CDS:
CAD62619.1,
BAB11849.1,
AAC83706.1,
AAH10107.1,
CAA10198.1,
EAW66248.1,
BAA87623.1,
CAB40136.1,
EAW66245.1,
BAA95120.1,
EAW66246.1,
EAW66247.1,
CAD61952.1,
AAH03062.1,
BAG36987.1,
ALQ33918.1
Ensembl_TRS:
ENST00000397528,
ENST00000397532,
ENST00000285850,
ENST00000674313,
ENST00000397529,
ENST00000555702
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380666,
ENSP00000501493,
ENSP00000380663,
ENSP00000380662,
ENSP00000451881,
ENSP00000285850
RefSeq:
XP_011535600.1,
XP_006720365.1,
XP_011535601.1,
NP_001119577.1,
NP_001119578.1,
NP_003973.3
|
| Others |
UniRef100:
UniRef100_Q9UM01
UniRef90:
UniRef90_Q9UM01
UniRef50:
UniRef50_Q9UM01
UniGene:
Hs.513147,
Hs.732349
CCDS:
CCDS9574.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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