| Type | Description |
|---|---|
| Definition | mitochondrial calcium uniporter |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | Structural insights into the Ca(2+)-dependent gating of the human mitochondrial calcium uniporter. | 32762847 |
| 2020-12-12 13:30:00 | MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization. | 33067576 |
| 2020-11-21 13:30:00 | MCU deficiency blocks cell proliferation by disrupting cytoplasmic Ca2+ transients due to altered Drp1 hospitalization. | 31907514 |
| 2020-04-25 12:08:00 | MICU1 confers Ca(2+)-dependent gating of the uniporter by blocking/unblocking MCU. | 30638448 |
| 2020-02-29 11:29:00 | These observations suggest that macrophage MCU-mediated metabolic reprogramming contributes to fibrotic repair after lung injury. | 31473487 |
| Type | IDs |
|---|---|
| Synonymous | C10orf42, CCDC109A, HsMCU |
| Gene |
UniProtKB-ID:
MCU_HUMAN
UniprotKB:
Q8NE86
UniParc:
UPI00004A2900,
UPI000049DCFC,
UPI000006F233
EMBL:
AC069548,
AK128016,
AC016542,
BC010682,
BC034235,
AK315519,
CH471083
Ensembl:
ENSG00000156026
KO:
hsa:90550
|
| Nucleutide sequences |
EMBL-CDS:
AAH34235.1,
EAW54461.1,
AAH10682.1,
BAG54619.1,
BAG37900.1
Ensembl_TRS:
ENST00000536019,
ENST00000357157,
ENST00000373053
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440913,
ENSP00000362144,
ENSP00000349680
RefSeq:
NP_001257609.1,
XP_016872371.1,
NP_001257608.1,
NP_612366.1
|
| Others |
UniRef100:
UniRef100_Q8NE86
UniRef90:
UniRef90_Q8NE86
UniRef50:
UniRef50_Q8NE86
UniGene:
Hs.591366
CCDS:
CCDS7317.1,
CCDS59218.1,
CCDS59219.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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