| Type | Description |
|---|---|
| Definition | SH2 domain containing 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response. | 33046503 |
| 2020-06-27 11:30:00 | The ITK SH3 and LCK SH3 domains can both competefor and simultaneously bind to adjacent binding sites on TSAD encompassing aa 242-268. | 31484725 |
| 2017-04-08 12:15:00 | Data indicate that the T cell-specific adaptor protein (TSAd) SH2 domain interacts with CD6 antigen and linker for activation of T cells protein (LAT) phosphotyrosine (pTyr) peptides. | 27896837 |
| 2016-03-12 10:40:00 | TSAD binds to and co-localizes with Nck. Expression of TSAD increases both Nck-Lck and Nck-SLP-76 interaction in T cells. | 26163016 |
| 2015-08-15 11:20:00 | The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. | 25492967 |
| Type | IDs |
|---|---|
| Synonymous | F2771, SCAP, TSAD, VRAP |
| Gene |
UniProtKB-ID:
SH22A_HUMAN,
Q5UBZ3_HUMAN,
Q5UBZ2_HUMAN
UniprotKB:
Q9NP31,
Q5UBZ3,
Q5UBZ2
UniParc:
UPI000013C54B,
UPI0000F534AD,
UPI00004525CD,
UPI0000F534AC,
UPI000002B38E,
UPI0000458899
EMBL:
AJ000553,
AK222737,
BC012107,
AF097744,
AL590666,
AY763098,
AY763100,
AL158169,
AY763099,
AF106072,
AF051325
Ensembl:
ENSG00000027869
KO:
hsa:9047
|
| Nucleutide sequences |
EMBL-CDS:
AAF43260.1,
AAV34675.1,
CAA04185.1,
AAF69027.1,
AAH12107.1,
BAD96457.1,
AAC99298.1,
AAV34673.1,
AAV34674.1
Ensembl_TRS:
ENST00000368199,
ENST00000392306,
ENST00000368198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376123,
ENSP00000357181,
ENSP00000357182
RefSeq:
XP_016858255.1,
NP_003966.2,
XP_016858256.1,
XP_016858253.1,
NP_001154913.1,
XP_006711678.1,
NP_001154914.1,
NP_001154915.1,
XP_016858252.1,
XP_016858251.1,
XP_016858254.1,
NP_001154916.1
|
| Others |
UniRef100:
UniRef100_Q9NP31,
UniRef100_Q5UBZ3,
UniRef100_Q5UBZ2
UniRef90:
UniRef90_Q9NP31-2,
UniRef90_Q9NP31
UniRef50:
UniRef50_Q9NP31
UniGene:
Hs.103527
CCDS:
CCDS53380.1,
CCDS1159.1,
CCDS53381.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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