| Type | Description |
|---|---|
| Definition | docking protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 10:22:00 | Decreased DOK1/2 expressions associated with their promoter hypermethylations predict adverse prognosis in AML. | 29150948 |
| 2019-03-16 12:12:00 | DOK2 overexpression in different brain regions is associated with poor prognosis in astrocytoma clinical cases. | 27975172 |
| 2017-10-14 13:05:00 | In this report, the authors demonstrated that the cellular adaptor proteins Dok-2 and Dok-1 are tyrosine phosphorylated upon herpes simplex virus 1 infection. In addition, herpes simplex virus 1 induced the selective degradation of Dok-2. Finally, Dok-2 interacts with herpes simplex virus 1 VP11/12, and that herpes simplex virus 1-induced tyrosine phosphorylation and degradation of Dok-2 require VP11/12. | 28841444 |
| 2016-09-24 10:53:00 | DOK2 and DOK3 expression was significantly reduced in HTLV-1-infected T cells. | 27265473 |
| 2015-04-11 12:35:00 | point mutations in DOK1 and DOK2 genes are detected with low frequency in chronic myelomonocytic leukemia but may have consequences for the function of the DOK2 PTB domain | 25252871 |
| Type | IDs |
|---|---|
| Synonymous | p56DOK, p56dok-2 |
| Gene |
UniProtKB-ID:
DOK2_HUMAN,
B4DKQ6_HUMAN
UniprotKB:
O60496,
B4DKQ6
UniParc:
UPI000006F1DB,
UPI00017A749F
EMBL:
BC032623,
AK296671,
AF034970
Ensembl:
ENSG00000147443
KO:
hsa:9046
|
| Nucleutide sequences |
EMBL-CDS:
AAH32623.1,
AAC13265.1,
BAG59268.1
Ensembl_TRS:
ENST00000276420
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000276420
RefSeq:
XP_005273737.1,
NP_003965.2,
NP_958728.1,
NP_001304729.1
|
| Others |
UniRef100:
UniRef100_B4DKQ6,
UniRef100_O60496
UniRef90:
UniRef90_O60496,
UniRef90_B4DKQ6
UniRef50:
UniRef50_B4DKQ6,
UniRef50_O60496
UniGene:
Hs.71215
CCDS:
CCDS6016.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员