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90427 BMF

90427

BMF

Bcl2 modifying factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition Bcl2 modifying factor

研究结论

Date Results Publications
2020-09-05 13:59:00 Characterization of an alternative BAK-binding site for BH3 peptides. 32620849
2017-11-18 13:44:00 The findings are consistent with rs539846 influencing chronic lymphocytic leukemia (CLL) susceptibility through differential RELA binding, with direct modulation of BMF expression impacting on anti-apoptotic BCL2, a hallmark of oncogenic dependency in CLL. 27524613
2017-07-29 13:11:00 Reciprocal regulation of BMF and BIRC5 is linked to Eomes overexpression in colorectal cancer. 27539959
2017-07-22 11:12:00 Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression 27899442
2016-05-14 10:52:00 these findings suggest that p53-R273H can specifically drive AKT signaling and suppress BMF expression, resulting in enhanced cell survivability and anoikis resistance. 26181206

名称对应

Type IDs
Gene
UniProtKB-ID: BMF_HUMAN
UniprotKB: Q96LC9
UniParc: UPI00001A36E9, UPI0000071AC6, UPI00001A36E8
EMBL: AY029254, AY222040, BC069328, BC060783, BC069505, BC070043, BC104985, BC104983, AK024472, AY222041
Ensembl: ENSG00000104081
KO: hsa:90427
Nucleutide sequences
EMBL-CDS: BAB15762.1, AAP22965.1, AAH70043.2, AAI04984.1, AAI04986.1, AAP22966.1, AAH69505.1, AAH69328.1, AAH60783.1, AAK38748.1
Ensembl_TRS: ENST00000558774, ENST00000431415, ENST00000354670, ENST00000561360, ENST00000559701, ENST00000561282, ENST00000397573
Protein sequencees
Ensembl_PRO: ENSP00000453919, ENSP00000380703, ENSP00000453913, ENSP00000453522, ENSP00000396511, ENSP00000346697, ENSP00000453892
RefSeq: NP_277038.1, NP_001003943.1, NP_001003942.1, NP_001003940.1
Others
UniRef100: UniRef100_Q96LC9
UniRef90: UniRef90_Q96LC9
UniRef50: UniRef50_Q96LC9
UniGene: Hs.591104
CCDS: CCDS32196.1, CCDS45223.1, CCDS10052.1

全选

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