| Type | Description |
|---|---|
| Definition | kinetochore localized astrin (SPAG5) binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:08:00 | Recurrent somatic mutation p.Ala40Glu in KNSTRN gene is associated with basal proliferating actinic keratosis in accordance with invasive squamous cell cardinomas. This supports the impact of basal proliferative pattern in terms of progression | 30972880 |
| 2018-06-16 11:17:00 | The authors show that the Astrin-SKAP complex binds synergistically to microtubules with the Ndc80 complex to form an integrated interface. | 28841134 |
| 2018-06-16 10:40:00 | GSK3beta-SKAP-Kif2b signaling axis constitutes a dynamic link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. | 27982129 |
| 2017-11-18 12:49:00 | Data show that aurora-B regulates end-on conversion in human cells and indicate a late role for protein (Astrin)-SKAP complex in the end-on conversion process. | 28751710 |
| 2016-10-22 11:01:00 | KNSTRN Mutation, a Cutaneous Squamous Carcinoma-Specific Mutation is associated with Solid Tumors and Leukemias. | 26433880 |
| Type | IDs |
|---|---|
| Synonymous | C15orf23, HSD11, SKAP, TRAF4AF1 |
| Gene |
UniProtKB-ID:
SKAP_HUMAN
UniprotKB:
Q9Y448
UniParc:
UPI000016074A,
UPI0000E59BC9,
UPI0000E59BC7
EMBL:
CR611451,
AK301887,
AY652615,
AC013356,
CR602848,
BC045739,
BC107802,
BC064344,
BC118639,
BC014060,
U81002,
BC004543,
BC118559
Ensembl:
ENSG00000128944
KO:
hsa:90417
|
| Nucleutide sequences |
EMBL-CDS:
AAI07803.1,
AAT66172.1,
AAH04543.1,
AAH45739.1,
AAD24201.1,
AAH64344.1,
AAI18640.1,
AAI18560.1,
BAG63319.1,
AAH14060.1
Gene_ORFName:
HSD11
Ensembl_TRS:
ENST00000249776,
ENST00000448395,
ENST00000416151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000391233,
ENSP00000393001,
ENSP00000249776
RefSeq:
NP_001136233.1,
NP_001136234.1,
NP_150628.3
|
| Others |
UniRef100:
UniRef100_Q9Y448
UniRef90:
UniRef90_Q9Y448
UniRef50:
UniRef50_Q9Y448
UniGene:
Hs.525796
CCDS:
CCDS42021.1,
CCDS45227.1,
CCDS45226.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员