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90379 DCAF15

90379

DCAF15

DDB1 and CUL4 associated factor 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition DDB1 and CUL4 associated factor 15

研究结论

Date Results Publications
2020-04-25 12:42:00 aryl-sulfonamides neo-functionalize a shallow, non-conserved pocket on DCAF15 to selectively bind and degrade RBM39 and the closely related splicing factor RBM23 without the requirement for a high-affinity ligand 31686031
2020-04-25 12:29:00 structural and mutational analysis of how indisulam mediates the DCAF15-RBM39 interaction 31819272
2017-12-23 11:23:00 DCAF15 expression may be a useful biomarker to guide clinical trials of splicing inhibitor sulfonamides(SPLAMs). 28302793

名称对应

Type IDs
Synonymous C19orf72
Gene
UniProtKB-ID: DCA15_HUMAN
UniprotKB: Q66K64
UniParc: UPI0000203531
EMBL: BC013280, BC080575, BC002926, CH471106, AK093072
Ensembl: ENSG00000132017, ENSG00000288453
KO: hsa:90379
Nucleutide sequences
EMBL-CDS: EAW84386.1, BAG52648.1, AAH80575.1, AAH13280.2, AAH02926.2
Ensembl_TRS: ENST00000672437, ENST00000254337
Protein sequencees
Ensembl_PRO: ENSP00000500158, ENSP00000254337
RefSeq: NP_612362.2
Others
UniRef100: UniRef100_Q66K64
UniRef90: UniRef90_Q66K64
UniRef50: UniRef50_Q66K64
UniGene: Hs.443636
CCDS: CCDS32926.1

全选

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研究热度

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