| Type | Description |
|---|---|
| Definition | OTU deubiquitinase with linear linkage specificity |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | of OTULIN Regulates Ubiquitin Dynamics and | 31825842 |
| 2020-09-12 16:03:00 | ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/beta-catenin activation to enhance drug resistance in breast cancers. | 32770022 |
| 2020-01-11 11:36:00 | Authors define an additional, non-catalytic function of OTULIN in the regulation of SNX27-retromer assembly and recycling to the cell surface. | 31541095 |
| 2018-06-09 10:39:00 | results establish a role for the linear Ubiquitin coat around cytosolic S. Typhimurium as the local NF-kappaB signalling platform and provide insights into the function of OTULIN in NF-kappaB activation during bacterial pathogenesis | 28481361 |
| 2018-02-03 10:11:00 | Biallelic hypomorphic mutations in OTULIN define otulipenia, an early-onset autoinflammatory disease. | 27559085 |
| Type | IDs |
|---|---|
| Synonymous | AIPDS, FAM105B, GUM |
| Gene |
UniProtKB-ID:
OTUL_HUMAN
UniprotKB:
Q96BN8
UniParc:
UPI0000374C00
EMBL:
CH471102,
BC007706,
AC010491,
AK092203,
BC015392
Ensembl:
ENSG00000154124
KO:
hsa:90268
|
| Nucleutide sequences |
EMBL-CDS:
AAH07706.3,
EAX08039.1,
BAC03828.1,
EAX08038.1,
AAH15392.2
Ensembl_TRS:
ENST00000284274
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000284274
RefSeq:
XP_016865504.1,
XP_011512453.1,
NP_612357.4,
XP_011512454.1,
XP_011512456.1
|
| Others |
UniRef100:
UniRef100_Q96BN8
UniRef90:
UniRef90_Q96BN8
UniRef50:
UniRef50_Q96BN8
UniGene:
Hs.406335
CCDS:
CCDS43302.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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