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9026 HIP1R

9026

HIP1R

huntingtin interacting protein 1 related

protein-coding

Homo sapiens

基因描述

Type Description
Definition huntingtin interacting protein 1 related

研究结论

Date Results Publications
2020-03-07 11:54:00 There is coordinated action of myosin VI and CLCa at the apical surface where these proteins are essential for fission of clathrin-coated pits. Myosin VI and Huntingtin-interacting protein 1-related protein (Hip1R) are mutually exclusive interactors with CLCa, and suggest a model for the sequential function of myosin VI and Hip1R in actin-mediated clathrin-coated vesicle budding. 31672988
2019-05-11 10:56:00 HIP1R is a natural regulator of PD-L1 lysosomal degradation, and the functions of HIP1R relied on two sequence stretches- one involved in the interaction with PD-L1 and for the sorting to the lysosome. 30397328
2017-09-02 11:04:00 HIP1R rescued miR-23b/-27b-mediated repression of migration in prostate cancer cells. HIP1R mRNA levels were decreased in seminal vesicle tissue from mice bearing miR-23b/-27b-transduced prostate cancer cell xenografts compared with scrambled controls, suggesting HIP1R is a key functional target of miR-23b/-27b. 26898757
2016-04-23 10:36:00 our findings support the conclusion that the rs12817488 in CCDC62/HIP1R polymorphism may increase the risk of Parkinson's disease in the Chinese Han population. 25818163
2016-04-23 10:20:00 We conclude that HIP1R expression is strongly indicative of survival in diffuse large B-cell lymphoma 26341140

名称对应

Type IDs
Synonymous HIP12, HIP3, ILWEQ
Gene
UniProtKB-ID: HIP1R_HUMAN, B4DPL0_HUMAN, B3KQW8_HUMAN
UniprotKB: O75146, B4DPL0, B3KQW8
UniParc: UPI00001FB8E6, UPI00017A79DF, UPI000012C72C, UPI0000371F43
EMBL: AK090537, AB013384, AK298387, BC067085, AB014555, AC027290
Ensembl: ENSG00000130787
KO: hsa:9026
Nucleutide sequences
EMBL-CDS: BAA33713.1, AAH67085.1, BAA31630.1, BAG60622.1, BAG52180.1
Ensembl_TRS: ENST00000253083
Protein sequencees
Ensembl_PRO: ENSP00000253083
RefSeq: NP_001290028.1, XP_011537265.1, XP_024305038.1, NP_003950.1, NP_001290026.1
Others
UniRef100: UniRef100_O75146, UniRef100_O75146-2, UniRef100_B3KQW8
UniRef90: UniRef90_O75146-2, UniRef90_O75146
UniRef50: UniRef50_O75146, UniRef50_O75146-2
UniGene: Hs.524815, Hs.714965
CCDS: CCDS31922.1

全选

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