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9025 RNF8

9025

RNF8

ring finger protein 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 8

研究结论

Date Results Publications
2021-03-13 13:20:00 RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells. 32502756
2020-09-12 16:05:00 RNF8 has both KU-dependent and independent roles in chromosomal break repair. 32427332
2020-07-25 12:12:00 during HTLV-1 infection, Tax activates RNF8 to assemble nuclear K63-pUbs that sequester DDR factors in Tax speckles, disrupting DDR signaling and DSB repair. 32453758
2020-04-18 12:36:00 These findings suggested that RNF8 promotes efficient DNA double-strand break repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60. 32031738
2020-02-15 11:52:00 the miR-214-RNF8 axis has a role in epithelial-mesenchymal transition in breast cancer; miR-214 acts as a tumor suppressor 31294443

名称对应

Type IDs
Synonymous hRNF8
Gene
UniProtKB-ID: RNF8_HUMAN
UniprotKB: O76064
UniParc: UPI000013437B, UPI00001BC00A, UPI0001AE4F33
EMBL: BC007517, AL096712, AK298319, AB014546, AB012770, BT007446, CH471081, AK222765, AF334675
Ensembl: ENSG00000112130
KO: hsa:9025
Nucleutide sequences
EMBL-CDS: AAQ14887.1, AAP36114.1, BAD96485.1, BAG60572.1, EAX03945.1, EAX03944.1, BAA33557.1, AAH07517.1, BAA31621.2
Ensembl_TRS: ENST00000229866, ENST00000469731, ENST00000373479
Protein sequencees
Ensembl_PRO: ENSP00000418879, ENSP00000362578, ENSP00000229866
RefSeq: XP_006715304.1, NP_898901.1, XP_006715305.1, XP_016866951.1, XP_016866953.1, NP_003949.1, XP_016866952.1
Others
UniRef100: UniRef100_O76064
UniRef90: UniRef90_O76064
UniRef50: UniRef50_O76064
UniGene: Hs.485278
CCDS: CCDS4834.1, CCDS4833.1

全选

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