| Type | Description |
|---|---|
| Definition | unc-5 netrin receptor A |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 13:19:00 | These studies reveal an unexpected role of the axon guidance receptor UNC5A in fine-tuning ERalpha and EGFR signaling and the luminal progenitor status of hormone-sensitive breast cancers. Furthermore, UNC5A knockdown cells provide an ideal model system to investigate metastasis of ERalpha(+) breast cancers | 29720215 |
| 2019-01-19 10:51:00 | The results suggest that netrin-1 promotes glioma cell proliferation by activating NF-kappaB signaling via UNC5A. | 28710382 |
| 2018-02-24 11:45:00 | Such data indicate that cooperation between the UPR and UNC5A depletion as previously observed by ourselves in HCC patients samples may foster liver cancer development and growth. | 29277614 |
| 2017-12-09 11:44:00 | UNC5A is capable of impeding autophagy and promoting HCV restriction through specific impact on virion infectivity, in a cell death-independent and DAPK-related manner. | 28783179 |
| 2015-12-26 12:05:00 | FANCC interferes with UNC5A's functions in apoptosis and suggest that FANCC may participate in developmental processes through association with the dependence receptor UNC5A. | 24676280 |
| Type | IDs |
|---|---|
| Synonymous | UNC5H1 |
| Gene |
UniProtKB-ID:
UNC5A_HUMAN,
H0Y8R2_HUMAN
UniprotKB:
Q6ZN44,
H0Y8R2
UniParc:
UPI000016139D,
UPI0000047F37,
UPI000045738E,
UPI000004B685
EMBL:
BC009333,
BC157824,
AK131380,
AC091897,
BC033727,
AB075856,
AC091902,
AC027318
Ensembl:
ENSG00000113763
KO:
hsa:90249
|
| Nucleutide sequences |
EMBL-CDS:
AAI57825.1,
AAH09333.2,
BAD18531.1,
BAB85562.1
Ensembl_TRS:
ENST00000329542,
ENST00000509580
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000332737,
ENSP00000421795
RefSeq:
XP_011532988.1,
NP_588610.2,
XP_006714990.1,
XP_011532989.1,
XP_006714991.1
|
| Others |
UniRef100:
UniRef100_H0Y8R2,
UniRef100_Q6ZN44
UniRef90:
UniRef90_Q6ZN44,
UniRef90_Q8K1S4
UniRef50:
UniRef50_O08722,
UniRef50_O08721
UniGene:
Hs.33191
CCDS:
CCDS34299.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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