| Type | Description |
|---|---|
| Definition | heparan sulfate 6-O-sulfotransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 11:21:00 | we identified a novel c.916G>C variant in the HS6ST2 gene. The mutation caused a significantly reduction in HS6ST2 6-O-sulfotransferase activity and was associated with a previously undescribed form of syndromic XLID with severe congenital myopia | 30471091 |
| 2019-11-09 12:19:00 | downregulated HS6ST2 targeted by miR-23b-3p promotes matrix degradation by activating p38 MAPK in chondrocytes and OA cartilage. | 29899528 |
| 2018-07-07 10:16:00 | RT-PCR analysis showed that the overall transcriptional activity of the main Heparan Sulfate biosynthesis-involved genes (EXT1, EXT2, NDST1, NDST2, GLCE, HS2ST1, HS3ST1, HS3ST2, HS6ST1, HS6ST2, SULF1, SULF2, HPSE) was decreased by 1.5-2-fold in Grade II-III glioma. | 29104277 |
| 2014-06-21 11:11:00 | HS6ST-1 and HS6ST-2 have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF signaling and subsequent expression of angiogenic cytokines by cancer cells | 24563483 |
| 2011-07-23 10:31:00 | HS6ST2 knockdown disrupts epithelial-mesenchymal transition and suggesets that HS6ST2 potentiates Notch signaling in pancreatic cancer cells. | 21443520 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
H6ST2_HUMAN
UniprotKB:
Q96MM7
UniParc:
UPI0000046171,
UPI0000049037,
UPI0000E59259,
UPI00005B733E
EMBL:
AL022159,
AL022309,
BC037325,
AK027720,
BC110620,
Z81365,
AK075402,
AL831923,
Z86064,
AK056706,
AB067776,
BC094718,
BC110621,
AB067777,
Z82205
Ensembl:
ENSG00000171004
KO:
hsa:90161
|
| Nucleutide sequences |
EMBL-CDS:
BAC11597.1,
BAC07183.1,
CAX30811.1,
BAC07184.1,
AAI10622.1,
AAH37325.1,
BAB55322.1,
AAH94718.1,
AAI10621.1,
BAB71260.1,
CAI42774.1,
CAX30812.1,
CAD38583.1,
CAI42775.1
Gene_ORFName:
PSEC0092
Ensembl_TRS:
ENST00000370836,
ENST00000370833,
ENST00000406696,
ENST00000521489
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359873,
ENSP00000429473,
ENSP00000359870,
ENSP00000384013
RefSeq:
NP_001070656.1,
XP_011529710.1,
XP_011529708.1,
XP_011529709.1,
NP_671704.3,
XP_016885434.1,
XP_005262548.1,
XP_016885435.1
|
| Others |
UniRef100:
UniRef100_Q96MM7
UniRef90:
UniRef90_Q96MM7
UniRef50:
UniRef50_Q96MM7
UniGene:
Hs.385956
CCDS:
CCDS48169.1,
CCDS48170.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员