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9014 TAF1B

9014

TAF1B

TATA-box binding protein associated factor, RNA polymerase I subunit B

protein-coding

Homo sapiens

基因描述

Type Description
Definition TATA-box binding protein associated factor, RNA polymerase I subunit B

研究结论

Date Results Publications
2016-07-02 10:20:00 AEP coactivator complex facilitates the initiation of RNAP2-dependent transcription via SL1 activity by loading TBP onto the TATA element. 26593443
2016-04-09 10:05:00 hCdc14B promotes reactivation of rDNA transcription by dephosphorylating TAFI110. SIRT1 becomes transiently enriched in nucleoli at the onset of mitosis. SIRT1 deacetylates TAFI68 destabilizing SL1 binding to the rDNA promoter 26023773
2011-10-01 10:30:00 findings show that Rrn7, a subunit of the yeast Pol I core factor, and its human ortholog TAF1B are TFIIB-like factors 21921198
2011-10-01 10:30:00 TAF1B, a subunit of SL1, is structurally related to TFIIB/TFIIB-like proteins; SL1, essential for Pol I recruitment to rRNA gene promoter, also has an essential postpolymerase recruitment role, operating through TAF1B 21921199
2010-06-30 22:05:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous MGC:9349, RAF1B, RAFI63, SL1, TAFI63
Gene
UniProtKB-ID: TAF1B_HUMAN
UniprotKB: Q53T94
UniParc: UPI0000208E44, UPI0002064F91, UPI0000E825D1
EMBL: L39061, AC010969, BC018137, AK295402
Ensembl: ENSG00000115750
KO: hsa:9014
Nucleutide sequences
EMBL-CDS: AAX93272.1, AAA62863.1, BAG58354.1, AAH18137.1
Ensembl_TRS: ENST00000263663
Protein sequencees
Ensembl_PRO: ENSP00000263663
RefSeq: NP_005671.3, XP_011508712.1, NP_001305906.1, NP_001305905.1, XP_024308977.1, XP_011508713.1
Others
UniRef100: UniRef100_Q53T94
UniRef90: UniRef90_Q53T94
UniRef50: UniRef50_Q53T94
UniGene: Hs.584833
CCDS: CCDS33143.1

全选

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