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9013 TAF1C

9013

TAF1C

TATA-box binding protein associated factor, RNA polymerase I subunit C

protein-coding

Homo sapiens

基因描述

Type Description
Definition TATA-box binding protein associated factor, RNA polymerase I subunit C

研究结论

Date Results Publications
2019-07-27 13:02:00 Observed significantly higher TAF1C expression in patients with type 2 diabetes mellitus (T2DM), suggesting a role for increased protein synthesis in T2DM. 31039436
2016-04-09 10:05:00 hCdc14B promotes reactivation of rDNA transcription by dephosphorylating TAFI110. SIRT1 becomes transiently enriched in nucleoli at the onset of mitosis. SIRT1 deacetylates TAFI68 destabilizing SL1 binding to the rDNA promoter 26023773
2015-09-05 11:51:00 Our results indicate that TAF1C gene harboured not only somatic frameshift mutations but also the mutational ITH, which together might play a role in tumourigenesis of gastric and colorectal cancer. 25551296
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20800603
2010-09-15 22:06:00 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) 20663923

名称对应

Type IDs
Synonymous MGC:39976, SL1, TAFI110, TAFI95
Gene
UniProtKB-ID: TAF1C_HUMAN, B3KUE8_HUMAN
UniprotKB: Q15572, B3KUE8
UniParc: UPI000178E053, UPI000015FC5C, UPI0000167B3A, UPI0001B30128, UPI000047DC02, UPI0000E02E3A
EMBL: AC009123, AK299347, AK304261, BC028131, AK299060, AK097031, AY158985, L39059, AB209594, AK315982
Ensembl: ENSG00000103168
KO: hsa:9013
Nucleutide sequences
EMBL-CDS: BAH13010.1, BAD92831.1, BAH14353.1, AAH28131.1, AAA62861.1, BAH12941.1, BAH14144.1, AAN38818.1, BAG53410.1
Ensembl_TRS: ENST00000341690, ENST00000567759, ENST00000570117, ENST00000541676, ENST00000566732
Protein sequencees
Ensembl_PRO: ENSP00000345305, ENSP00000455247, ENSP00000455265, ENSP00000437900, ENSP00000455933
RefSeq: NP_001230087.1, NP_647610.3, NP_001230085.2, NP_001230088.1, XP_006721388.1, XP_016879335.1, XP_006721389.1, XP_005256283.1, XP_016879334.1, NP_005670.4, NP_001230086.1, XP_005256284.1, NP_001230089.1, XP_016879336.1
Others
UniRef100: UniRef100_B3KUE8, UniRef100_Q15572
UniRef90: UniRef90_B3KUE8, UniRef90_Q15572
UniRef50: UniRef50_Q15572, UniRef50_B3KUE8
UniGene: Hs.153022
CCDS: CCDS58489.1, CCDS58488.1, CCDS45535.1, CCDS32496.1

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