| Type | Description |
|---|---|
| Definition | pleckstrin homology like domain family B member 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-05 12:56:00 | Prickle1 localized to the membrane through its farnesyl moiety, and the membrane localization was necessary for Prickle1 to regulate migration, to bind to CLASPs and LL5beta, and to promote microtubule targeting of focal adhesions. | 27378169 |
| 2017-06-24 12:19:00 | Collectively, our findings present the first to elucidate that miR-29c is a direct p53 target gene, and also identify PHLDB2 as an important miR-29c target gene involved in colon cancer metastasis. | 28392396 |
| 2015-08-15 10:56:00 | Liprin-alpha1, ERC1a and LL5 also define new highly polarized and dynamic cytoplasmic structures uniquely localized near the protruding cell edge | 24982445 |
| 2013-12-21 10:48:00 | These and other LL5beta-interacting proteins are associated with conventional podosomes in macrophages and podosome-like invadopodia in fibroblasts, strengthening the close relationship between synaptic and non-synaptic podosomes. | 23525008 |
| 2013-09-14 11:06:00 | minor allele, A, intronic single nucleotide polymorphism 'rs951660'in PHLDB2 might induce a delayed splicing and increase the susceptibility to Vascular dementia | 22111664 |
| Type | IDs |
|---|---|
| Synonymous | LL5b, LL5beta |
| Gene |
UniProtKB-ID:
PHLB2_HUMAN
UniprotKB:
Q86SQ0
UniParc:
UPI000006E25E,
UPI00006275DB,
UPI0000457152
EMBL:
AF506820,
AB209903,
CH471052,
BC150210,
BC069194,
AJ496194,
AK092996,
AK096151,
CR749654,
BC142678
Ensembl:
ENSG00000144824
KO:
hsa:90102
|
| Nucleutide sequences |
EMBL-CDS:
BAC04713.1,
BAC04014.1,
AAH69194.1,
BAD93140.1,
AAI50211.1,
AAI42679.1,
AAM33634.1,
CAH18447.1,
CAD42711.1,
EAW79690.1
Ensembl_TRS:
ENST00000393925,
ENST00000412622,
ENST00000481953,
ENST00000393923,
ENST00000431670
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418319,
ENSP00000405405,
ENSP00000377502,
ENSP00000377500,
ENSP00000405292
RefSeq:
NP_001127911.1,
NP_001127910.1,
NP_001127909.1,
NP_665696.1
|
| Others |
UniRef100:
UniRef100_Q86SQ0
UniRef90:
UniRef90_Q86SQ0
UniRef50:
UniRef50_Q86SQ0
UniGene:
Hs.603252,
Hs.679140
CCDS:
CCDS46886.1,
CCDS2962.1,
CCDS46885.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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