| Type | Description |
|---|---|
| Definition | thymidylate synthase |
| Date | Results | Publications |
|---|---|---|
| 2013-05-25 11:46:00 | Report the crystal structure of ThyX from H. pylori strain 26695 in complex with co-factor FAD and substrate dUMP at 2.5 A resolution. It consists of a 1.5 tetramer of ThyX with a total 1248 residues, six FAD and six dUMP molecules in an asymmetric unit. | 22512654 |
| 2013-04-20 15:04:00 | Cloned and purified the ThyX enzyme from H. pylori SS1 strain. Recombinant HpThyX showed maximum activity at pH 8.5, and K(m) values of the two substrates dUMP and CH(2) H(4) folate were determined to be 15.3 +/- 1.25 muM and 0.35 +/- 0.18 mM, respectively. | 21633987 |
| 2010-07-26 11:50:00 | Helicobacter pylori ThyX was purified and crystallized in complex with flavin adenine dinucleotide (FAD) and a diffraction data set was collected to 2.5 A resolution. | 20445247 |
| Type | IDs |
|---|