| Type | Description |
|---|---|
| Definition | suppressor APC domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | SAPCD2 promotes invasiveness and migration ability of breast cancer cells via YAP/TAZ. | 32329855 |
| 2020-08-12 15:44:00 | SAPCD2 is increased and positively associated with that of PXN-AS1-L isoform in nasopharyngeal carcinoma (NPC). Gain and loss-of-function experiments demonstrated that SAPCD2 promotes NPC cell proliferation, migration, and invasion. Furthermore, depletion of SAPCD2 significantly reverses the roles of PXN-AS1-L in promoting NPC cell proliferation, migration, and invasion in vitro, and NPC tumor growth in vivo. | 31173488 |
| 2019-02-23 11:20:00 | Study showed C9orf140 as a novel Axin1-interacting protein and a negative regulator of Wnt/beta-catenin signaling. It functions upstream of beta-catenin, outcompetes PP2A for binding to Axin1, influences the balance between phosphorylation and de-phosphorylation of beta-catenin compromising Wnt3A-induced beta-catenin accumulation. C9orf140 seems to mediate a negative feedback loop of Wnt/beta-catenin signaling by bindi... | 29531269 |
| 2017-02-25 11:00:00 | Data show that overexpressed p42.3 protein is correlated with gastric cancer cell proliferation, migration, and invasion, suggesting its use as a biological marker in gastric cancer. | 27449033 |
| 2017-02-18 12:23:00 | p42.3 protein was related to the occurrence and development of gastric carcinoma. | 27461626 |
| Type | IDs |
|---|---|
| Synonymous | C9orf140, p42.3 |
| Gene |
UniProtKB-ID:
SAPC2_HUMAN
UniprotKB:
Q86UD0
UniParc:
UPI00005A8C06
EMBL:
AL807752,
BC048267,
DQ150361
Ensembl:
ENSG00000186193
KO:
hsa:89958
|
| Nucleutide sequences |
EMBL-CDS:
AAZ39408.1,
AAH48267.1
Ensembl_TRS:
ENST00000409687
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386348
RefSeq:
NP_848543.2,
XP_011517482.1
|
| Others |
UniRef100:
UniRef100_Q86UD0
UniRef90:
UniRef90_Q86UD0
UniRef50:
UniRef50_Q86UD0
UniGene:
Hs.19322
CCDS:
CCDS7027.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员