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89953 KLC4

89953

KLC4

kinesin light chain 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition kinesin light chain 4

研究结论

Date Results Publications
2021-03-13 13:19:00 Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network. 32457423
2020-07-11 10:37:00 Findings indicate that SET domain protein 3 (SETD3) down-regulated the expression of kinesin light chain 4 (KLC4), contributing to the radiosensitivity of cervical cancer cells, suggesting targeting SETD3 might be a potential strategy for the clinical management of cervical cancer. 31235251
2016-10-08 11:04:00 The association of a KLC4 mutation with spastic paraplegia identifies a new locus for the disease. 26423925
2010-11-27 10:33:00 Data reveal aspects of the molecular mechanism of kinesin-8 motors that contribute to their unique dual motile and depolymerising functions, which are adapted to control microtubule length. 20818331

名称对应

Type IDs
Synonymous KNSL8, bA387M24.3
Gene
UniProtKB-ID: KLC4_HUMAN, A0A024RCZ8_HUMAN
UniprotKB: Q9NSK0, A0A024RCZ8
UniParc: UPI00001BDB9C, UPI00017A738C, UPI0001B04BB3, UPI0000073D03, UPI000023C3DA
EMBL: BC103727, AL162078, BC012357, BX640717, BC080637, CH471081, AK055293, AK094102, AL136304, AK127018, AK127894, AK297433, AK056393, AL355385
Ensembl: ENSG00000137171
KO: hsa:89953
Nucleutide sequences
EMBL-CDS: BAC86788.1, EAX04149.1, AAH12357.1, BAG59861.1, BAC87179.1, BAG51695.1, CAB82411.1, AAH80637.1, AAI03728.1, BAG51496.1, BAG52815.1, CAE45836.1, EAX04146.1, EAX04148.1
Gene_ORFName: hCG_17653
Ensembl_TRS: ENST00000259708, ENST00000453940, ENST00000458460, ENST00000479388, ENST00000467906, ENST00000347162, ENST00000394056
Protein sequencees
Ensembl_PRO: ENSP00000418759, ENSP00000410358, ENSP00000340221, ENSP00000259708, ENSP00000418031, ENSP00000377620, ENSP00000395806
RefSeq: XP_011513291.1, NP_958930.1, XP_016866946.1, NP_612352.1, NP_958929.1, NP_001275964.1, NP_001275963.1, NP_958931.1
Others
UniRef100: UniRef100_Q9NSK0
UniRef90: UniRef90_Q9NSK0
UniRef50: UniRef50_Q07866-9
UniGene: Hs.655123
CCDS: CCDS47429.1, CCDS4882.1, CCDS75459.1, CCDS4883.1

全选

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