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89941 RHOT2

89941

RHOT2

ras homolog family member T2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ras homolog family member T2

研究结论

Date Results Publications
2020-05-16 10:47:00 This study showed that RAB32 and RHOT2 were associated with aging, and that individuals exhibiting methylation levels of the RAB32 CpG site higher than 10% were observed more prone to disability than people with lower levels. 30787202
2019-12-21 10:57:00 MIRO2 regulate the spatial organization of mitochondria in a microtubule-dependent manner.GBF1 and Arf1 interact with Miro2. 30459446
2019-12-07 11:28:00 Miro1 binds directly to a C-terminal fragment of the Myo19 tail region and that Miro1/2 recruit the Myo19 tail. 30111583
2019-03-30 10:05:00 the data presented here indicate novel catalytic functions of human Miro atypical GTPases through altered catalytic mechanisms. 30513825
2018-06-09 10:08:00 Show that the C-terminal GTPase of the Parkin primary substrates Miro1 and Miro2 are necessary and sufficient for efficient ubiquitination. We present several new X-ray crystal structures of both Miro1 and Miro2 that reveal substrate recognition and ubiquitin transfer to be specific to particular protein domains and lysine residues. 27605430

名称对应

Type IDs
Synonymous ARHT2, C16orf39, MIRO-2, MIRO2, RASL
Gene
UniProtKB-ID: MIRO2_HUMAN
UniprotKB: Q8IXI1
UniParc: UPI000007310B, UPI0000D7E612
EMBL: AY207375, Z92544, BC004327, AJ517413, BC014942, AK090426, CH471112, AK024450, AE006464
Ensembl: ENSG00000140983
KO: hsa:89941
Nucleutide sequences
EMBL-CDS: BAC03407.1, AAH04327.1, CAD56957.1, BAB15740.1, AAK61240.1, AAP46090.1, AAH14942.1, EAW85763.1
Ensembl_TRS: ENST00000315082
Protein sequencees
Ensembl_PRO: ENSP00000321971
RefSeq: NP_001339207.1, NP_001339222.1, NP_001339220.1, XP_024306246.1, NP_001339214.1, NP_001339213.1, NP_001339217.1, NP_001339210.1, XP_024306248.1, NP_001339216.1, NP_001339219.1, NP_001339223.1, NP_001339205.1, NP_001339204.1, NP_001339208.1, NP_001339218.1, NP_001339206.1, XP_024306247.1, NP_001339215.1, NP_001339209.1, NP_001339212.1, NP_620124.1, XP_024306249.1, NP_001339211.1, NP_001339221.1
Others
UniRef100: UniRef100_Q8IXI1
UniRef90: UniRef90_Q8IXI1
UniRef50: UniRef50_Q8IXI1
UniGene: Hs.513242
CCDS: CCDS10417.1

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