| Type | Description |
|---|---|
| Definition | WD repeat domain 34 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 12:44:00 | Our study revealed that WDR34 promoted the progression of HCC by activating Wnt/beta-catenin signaling. | 30877610 |
| 2019-06-29 11:14:00 | these results indicate that incorporation of DYNLL1/DYNLL2 and DYNLRB1/DYNLRB2 into the dynein-2 complex via interactions with the WDR34 intermediate chain is crucial for dynein-2 function in retrograde ciliary protein trafficking. | 30649997 |
| 2019-02-16 10:20:00 | loss of function of dynein-2 WDR34 and WDR60 subunits leads to defects in transition zone architecture, as well as intraflagellar transport. | 30320547 |
| 2018-02-24 10:26:00 | In addition to the in vitro experiments, WDR34 negativity was correlated with tumoral growth of OSCCs. Our findings suggested that WDR34 inhibits OSCC progression and might be a potential tumor-suppressor molecule in OSCCs. | 29278705 |
| 2014-01-04 10:10:00 | In patients with short-rib polydactyly syndrome type III, primary cilia in WDR34 mutant fibroblasts were significantly shorter than normal and had a bulbous tip. | 24183449 |
| Type | IDs |
|---|---|
| Synonymous | DIC5, FAP133, SRTD11, bA216B9.3 |
| Gene |
UniProtKB-ID:
DC2I2_HUMAN
UniprotKB:
Q96EX3
UniParc:
UPI000045894D
EMBL:
BC011874,
AL356481,
BC001614
Ensembl:
ENSG00000119333
KO:
hsa:89891
|
| Nucleutide sequences |
EMBL-CDS:
AAH11874.2,
AAH01614.3
Ensembl_TRS:
ENST00000372715
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361800
RefSeq:
XP_011517481.1,
NP_443076.2
|
| Others |
UniRef100:
UniRef100_Q96EX3
UniRef90:
UniRef90_Q96EX3
UniRef50:
UniRef50_Q96EX3
UniGene:
Hs.495240
CCDS:
CCDS6906.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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