| Type | Description |
|---|---|
| Definition | phospholipase C zeta 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice. | 33626338 |
| 2021-02-13 13:29:00 | The alteration of PLCzeta protein expression in unexplained infertile and asthenoteratozoospermic patients: A potential effect on sperm fertilization ability. | 31736165 |
| 2021-02-06 13:57:00 | Increasing associations between defects in phospholipase C zeta and conditions of male infertility: not just ICSI failure? | 32285298 |
| 2021-02-06 13:56:00 | The identification of novel mutations in PLCZ1 responsible for human fertilization failure and a therapeutic intervention by artificial oocyte activation. | 31953539 |
| 2021-02-06 13:50:00 | Novel homozygous variations in PLCZ1 lead to poor or failed fertilization characterized by abnormal localization patterns of PLCzeta in sperm. | 31463947 |
| Type | IDs |
|---|---|
| Synonymous | NYD-SP27, PLC-zeta-1, PLCzeta, SPGF17 |
| Gene |
UniProtKB-ID:
PLCZ1_HUMAN,
A0A140VJR9_HUMAN,
A0A3B3ISW9_HUMAN
UniprotKB:
Q86YW0,
A0A140VJR9,
A0A3B3ISW9
UniParc:
UPI0000E447E2,
UPI000013D6F0,
UPI000000D7E3,
UPI000004EEA0
EMBL:
AF532185,
AK292279,
BC125067,
HM005458,
AC087242,
AY035866
Ensembl:
ENSG00000139151
KO:
hsa:89869
|
| Nucleutide sequences |
EMBL-CDS:
AAN71895.1,
AAI25068.1,
BAF84968.1,
AAK61372.1,
AEE61056.1
Ensembl_TRS:
ENST00000266505,
ENST00000539875,
ENST00000648272
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445026,
ENSP00000266505,
ENSP00000497636
RefSeq:
XP_016875674.1,
XP_024305021.1,
NP_149114.2,
XP_016875666.1,
XP_005253576.1,
XP_016875669.1,
XP_024305024.1,
XP_016875675.1,
XP_016875665.1,
XP_024305023.1,
XP_024305022.1,
NP_001317698.1,
XP_016875667.1,
NP_001317703.1,
XP_016875670.1,
XP_016875671.1,
XP_016875668.1,
XP_016875672.1,
XP_016875673.1
|
| Others |
UniRef100:
UniRef100_A0A3B3ISW9,
UniRef100_Q86YW0
UniRef90:
UniRef90_Q86YW0
UniRef50:
UniRef50_Q8K4D7
UniGene:
Hs.97542,
Hs.743832
CCDS:
CCDS8680.1,
CCDS81671.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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