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8986 RPS6KA4

8986

RPS6KA4

ribosomal protein S6 kinase A4

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribosomal protein S6 kinase A4

研究结论

Date Results Publications
2018-06-23 10:24:00 Two novel DMRs, located in RPS6KA4/MIR1237 and the AURKC promoter, were found to be hypermethylated in WT 28930610
2015-11-07 10:39:00 KSHV activates the MSK1/2-CREB1 pathway during primary infection and that it depends on this pathway for viral lytic replication. I 26109721
2014-08-23 10:53:00 Data suggest that MSK1 and MSK2 are the major CREB kinases in fibroblast-like synoviocytes from rheumatoid arthritis patients stimulated with lysophosphatidic acid and that phosphorylation of CREB1 at Ser-133 plays a significant role in IL-8 production. 24792438
2013-12-14 10:34:00 MSK1 and MSK2 are required for maximal TFF 1 induction. 23675462
2011-06-04 10:15:00 MSK2 functions as an adaptor in mediating PKR activation, apparently independent of its catalytic activity. 21385567

名称对应

Type IDs
Synonymous MSK2, RSK-B, S6K-alpha-4
Gene
UniProtKB-ID: KS6A4_HUMAN, B4DPV1_HUMAN, A0PJF8_HUMAN, E9PJN1_HUMAN
UniprotKB: O75676, B4DPV1, A0PJF8, E9PJN1
UniParc: UPI0000D49B37, UPI000046D37B, UPI000006F835, UPI00017A7787, UPI00004059E5
EMBL: AK292163, AK223561, AP003774, AJ010119, AF074715, CH471076, AK298507, BC028079
Ensembl: ENSG00000162302
KO: hsa:8986
Nucleutide sequences
EMBL-CDS: AAC67395.1, EAW74260.1, BAD97281.1, CAA09009.1, BAF84852.1, BAG60713.1, AAH28079.1
Ensembl_TRS: ENST00000334205, ENST00000528057
Protein sequencees
Ensembl_PRO: ENSP00000333896, ENSP00000435580
RefSeq: NP_001305290.1, NP_001006945.1, XP_005274437.1, NP_003933.1, XP_016874016.1, NP_001287731.1
Others
UniRef100: UniRef100_B4DPV1, UniRef100_O75676, UniRef100_E9PJN1
UniRef90: UniRef90_O75676, UniRef90_A0A3Q7TG80
UniRef50: UniRef50_O75676
UniGene: Hs.105584
CCDS: CCDS8073.1

全选

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