| Type | Description |
|---|---|
| Definition | sialic acid binding Ig like lectin 12 (gene/pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2013-09-07 11:12:00 | cardiovascular outcomes may differ based on SIGLEC12 genotype, and antihypertensive treatment strategy. | 23690342 |
| 2011-09-10 12:10:00 | SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. | 21555517 |
| 2010-09-15 22:05:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2010-09-15 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-04-07 21:39:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| Type | IDs |
|---|---|
| Synonymous | S2V, SIGLECL1, SLG, Siglec-XII |
| Gene |
UniProtKB-ID:
SIG12_HUMAN
UniprotKB:
Q96PQ1
UniParc:
UPI0000135992,
UPI000002B3BB
EMBL:
AF282256,
BC035809,
AF277806,
AY358140
Ensembl:
ENSG00000254521
KO:
hsa:89858
|
| Nucleutide sequences |
EMBL-CDS:
AAK51234.1,
AAH35809.2,
AAQ88507.1,
AAK51233.1,
AAK71521.1
Gene_ORFName:
UNQ9215/PRO34042
Ensembl_TRS:
ENST00000291707,
ENST00000598614
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000291707,
ENSP00000472873
RefSeq:
XP_011525743.1,
XP_011525744.1,
NP_443729.1,
NP_201586.1
|
| Others |
UniRef100:
UniRef100_Q96PQ1
UniRef90:
UniRef90_Q96PQ1
UniRef50:
UniRef50_Q96PQ1
UniGene:
Hs.249741
CCDS:
CCDS59416.1,
CCDS12833.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 23690342 |
Hypertension Caitrin W McDonough , Yan Gong , Sandosh Padmanabhan , Ben Burkley , Taimour Y Langaee , Olle Melander , Carl J Pepine , Anna F Dominiczak , Rhonda M Cooper-Dehoff , Julie A Johnson |
2013-07-01 |
A1BG,
F5,
SIGLEC12
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21555517 |
J. Biol. Chem. Nivedita Mitra , Kalyan Banda , Tasha K Altheide , Lana Schaffer , Teresa L Johnson-Pais , Joke Beuten , Robin J Leach , Takashi Angata , Nissi Varki , Ajit Varki |
2011-07-01 |
SIGLEC12
|
| 20628086 |
Diabetes Care Swneke D Bailey , Changchun Xie , Ron Do , Alexandre Montpetit , Rafael Diaz , Viswanathan Mohan , Bernard Keavney , Salim Yusuf , Hertzel C Gerstein , James C Engert , Sonia Anand , DREAM investigators |
2010-10-01 | - |
| 20237496 |
New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. S Davila , F E M Froeling , A Tan , C Bonnard , G J Boland , H Snippe , M L Hibberd , M Seielstad |
2010-04-01 |
SH2B3,
MICA,
NR1H3,
TSPAN2,
NAMPT,
PRG4,
KLRG1,
CD96,
EFS,
APC2,
LAMC3,
CRISP3,
TLR6,
CLEC10A,
SEMA4D,
CEBPG,
PROCR,
PRDX4,
IFI44,
CXCL13,
GNLY,
COLEC10,
SH2B2,
CD226,
TNFSF13B,
NFAT5,
KLRA1P,
CFHR4,
CFHR3,
C1QL1,
EDAR,
MAGED2,
PRDX3,
IFI44L,
LILRB5,
LILRB4,
LILRA1,
LILRA2,
DUS4L,
ESM1,
FGFR1OP,
FAF1,
CD160,
RASSF1,
IRAK3,
IL17F,
CHRM1,
CD300A,
COPE,
KIF12,
CMTM1,
SIGLEC11,
NLRP3,
TIRAP,
PGLYRP2,
PGLYRP3,
SLAMF6,
FCRL1,
FCRL3,
GBP4,
GBP5,
TNFRSF13C,
FOXP4,
IL22RA2,
DEFB118,
CLC,
ADD1,
SFXN4,
IFI27L1,
CCR3,
CCR4,
CCR5,
CCR7,
CCR8,
ACKR2,
CMKLR1,
CCDC78,
CD300LB,
OSCAR,
ANKLE1,
GABPB2,
CNTFR,
COL4A3,
COL4A4,
BPIFB6,
ZPLD1,
KLF6,
IL31RA,
PPARGC1B,
RAET1E,
ADORA2B,
SSC4D,
CR1,
PXDNL,
CR2,
CREB1,
CREM,
GAB3,
CRP
|
| 19913121 |
Am. J. Hum. Genet. Philippa J Talmud , Fotios Drenos , Sonia Shah , Tina Shah , Jutta Palmen , Claudio Verzilli , Tom R Gaunt , Jacky Pallas , Ruth Lovering , Kawah Li , Juan Pablo Casas , Reecha Sofat , Meena Kumari , Santiago Rodriguez , Toby Johnson , Stephen J Newhouse , Anna Dominiczak , Nilesh J Samani , Mark Caulfield , Peter Sever , Alice Stanton , Denis C Shields , Sandosh Padmanabhan , Olle Melander , Claire Hastie , Christian Delles , Shah Ebrahim , Michael G Marmot , George Davey Smith , Debbie A Lawlor , Patricia B Munroe , Ian N Day , Mika Kivimaki , John Whittaker , Steve E Humphries , Aroon D Hingorani , ASCOT investigators , NORDIL investigators , BRIGHT Consortium |
2009-11-01 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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