| Type | Description |
|---|---|
| Definition | kelch like family member 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 10:05:00 | Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2. | 29695787 |
| 2017-12-09 12:50:00 | KLHL6 was positive mainly in B-cell neoplasms of germinal center derivation, including 95% of follicular lymphomas (106/112) | 29140403 |
| 2017-12-02 11:10:00 | Abnormal expression of the KLHL6 oncogene promoted gastric cancer progression in vitro and in vivo, and its expression level in tumor tissue was found to be of prognostic value. | 29044464 |
| 2017-10-28 13:02:00 | report that KLHL6, which is recurrently mutated in B cell lymphomas, is an off-target of the normal somatic hypermutation process taking place in germinal center (GC) B cells leaving open whether, despite the lack of impact of Klhl6 deficiency on GC B cell expansion, mutants could contribute to the oncogenic process | 28807996 |
| 2010-01-21 00:00:00 | characterization of two genes expressed in centroblasts of human tonsils: deltex (Drosophila) homolog 1 (DTX1), which is related to the Notch pathway and a new Kelch-like protein, KLHL6 | 12617994 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KLHL6_HUMAN
UniprotKB:
Q8WZ60
UniParc:
UPI0000169CB9
EMBL:
AK097125,
AC069211,
AK314473,
BC032348,
AC092960,
AF441792,
CH471052
Ensembl:
ENSG00000172578
KO:
hsa:89857
|
| Nucleutide sequences |
EMBL-CDS:
AAL35594.1,
EAW78324.1,
AAH32348.1,
EAW78325.1,
BAG37078.1,
BAC04957.1
Ensembl_TRS:
ENST00000341319
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341342
RefSeq:
XP_011511576.1,
XP_011511575.1,
NP_569713.2
|
| Others |
UniRef100:
UniRef100_Q8WZ60
UniRef90:
UniRef90_Q8WZ60
UniRef50:
UniRef50_Q8WZ60
UniGene:
Hs.659147
CCDS:
CCDS3245.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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