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8985 PLOD3

8985

PLOD3

procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

研究结论

Date Results Publications
2020-09-05 13:55:00 Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma. 31446433
2020-06-13 13:05:00 These data are consistent with pathogenic variants in PLOD3 resulting in a clinically distinct Stickler-like syndrome with vascular complications and variable features of EDS and EB. Early identification of PLOD3 variants would improve monitoring for comorbidities and may avoid serious adverse ocular and vascular outcomes. 31129566
2020-04-11 12:38:00 PLOD3 siRNA suppresses radioresistance and chemoresistance by inducing apoptosis and renders PLOD3 as a candidate lung cancer biomarker. 30770789
2020-04-11 11:05:00 our results demonstrate the novel function of the collagen-like glycosylation of CCN1 and suggest that lysyl hydroxylase3-mediated glycosylation is important for CCN1 secretion. 31317175
2019-12-14 12:38:00 These results indicate that PLOD3 promotes lung cancer metastasis in a RAS-MAP kinase pathway-independent manner. Therefore, secreted PLOD3 serves as a potent inducer of lung cancer metastasis and a potential therapeutic target to enhance survival in lung cancer. 30442941

名称对应

Type IDs
Synonymous LH3
Gene
UniProtKB-ID: PLOD3_HUMAN, Q9UG85_HUMAN
UniprotKB: O60568, Q9UG85
UniParc: UPI0000046664, UPI00000706FA
EMBL: AC004876, BC011674, AF068229, AL049952, AK312743, CH471197, AF207069, AY220458, AF046889
Ensembl: ENSG00000106397
KO: hsa:8985
Nucleutide sequences
EMBL-CDS: AAF63701.1, AAD45831.1, AAC34808.1, EAW50205.1, BAG35613.1, AAC39753.1, AAH11674.1, AAO61775.1, CAB43221.1
Ensembl_TRS: ENST00000223127
Protein sequencees
Ensembl_PRO: ENSP00000223127
RefSeq: NP_001075.1
Others
UniRef100: UniRef100_Q9UG85, UniRef100_O60568
UniRef90: UniRef90_O60568, UniRef90_Q9UG85
UniRef50: UniRef50_O60568, UniRef50_A0A671V9C5
UniGene: Hs.153357
CCDS: CCDS5715.1

全选

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