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89849 ATG16L2

89849

ATG16L2

autophagy related 16 like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition autophagy related 16 like 2

研究结论

Date Results Publications
2020-06-20 10:49:00 Results found ATG16L2 rs10898880 was significantly associated with the occurrence of grade 3-4 oral mucositis and myelosuppression in nasopharyngeal carcinoma (NPC) patients treated with radiotherapy. 31692259
2019-04-20 10:46:00 Patients with the ATG16L2 rs10898880 CC variant genotype had a better LRFS, PFS, and OS (adjusted hazard ratio = 0.59, 0.64, and 0.64; 95% confidence interval: 0.45-0.79, 0.48-0.84, and 0.48-0.86; p = 0.0004, 0.002, and 0.003, respectively), but a greater risk for development of severe RP (adjusted hazard ratio = 1.80, 95% confidence interval: 1.04-3.12, p = 0.037) than did patients with AA/AC genotypes. 29454863
2017-07-22 11:27:00 ATG16L2 is a susceptibility gene for Crohn's disease in the Chinese population. The rs11235604 single nucleotide polymorphism is remarkably associated with downregulation of the expression of ATG16L2. 27611316
2017-07-08 10:15:00 A novel SNP-systemic lupus erythematosus association was identified between FCHSD2 and P2RY2, peaking at rs11235667 on a 33-kb haplotype upstream of ATG16L2. 26663301
2014-11-22 10:18:00 Atg16L2 may play an important role in autophagy of T cells and serve as a potential biomarker to predict clinical relapse of Multiple sclerosis 24406150

名称对应

Type IDs
Synonymous ATG16B, WDR80
Gene
UniProtKB-ID: A16L2_HUMAN, Q9H7Q5_HUMAN
UniprotKB: Q8NAA4, Q9H7Q5
UniParc: UPI0000070258, UPI0000140B06, UPI0000EE46F3, UPI000004D248
EMBL: CH471076, AK024423, AL832974, BC142718, BC137489, BC146660, AK093017, BC137490, AK090597, BC036713
Ensembl: ENSG00000168010
KO: hsa:89849
Nucleutide sequences
EMBL-CDS: CAH56355.1, EAW74876.1, AAI46661.1, AAI42719.1, BAC03485.1, AAH36713.1, AAI37490.1, BAC04021.1, AAI37491.1, EAW74874.1, BAB15713.1
Ensembl_TRS: ENST00000321297
Protein sequencees
Ensembl_PRO: ENSP00000326340
RefSeq: XP_006718796.1, NP_203746.1, XP_005274433.1, NP_001305695.1, XP_006718797.1, XP_006718795.1, XP_011543634.1, XP_011543636.1, XP_011543635.1
Others
UniRef100: UniRef100_Q9H7Q5, UniRef100_Q8NAA4
UniRef90: UniRef90_Q8NAA4, UniRef90_Q9H7Q5
UniRef50: UniRef50_Q8NAA4, UniRef50_Q9H7Q5
UniGene: Hs.653186
CCDS: CCDS31634.1

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