Type | Description |
---|---|
Definition | ATP binding cassette subfamily C member 10 |
Date | Results | Publications |
---|---|---|
2019-07-20 12:59:00 | In the cancer cell lines, only rs2125739 of ABCC10 gene was significantly associated with docetaxel cytotoxicity, and this was confirmed in the genome-edited cell line. In the non-small cell lung cancer (NSCLC) patients, there were no significant differences related to rs2125739 genotype in terms of response rate, progression free and overall survival. However, this SNP was associated with grade 3/4 neutropenia. | 30890141 |
2018-03-03 11:25:00 | FOXM1 promotes 5-FU resistance by up-regulating ABCC10 expression in colorectal tumor cells. | 28051999 |
2017-08-12 12:07:00 | It is thus inferred, that ABCC10 expression in CWR22Rv1 cells is not S phase-specific but is primarily associated with cell proliferation. | 28612064 |
2017-06-10 11:02:00 | The present study shows that the protein expression of ABCC10 significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients | 27468921 |
2016-05-21 11:35:00 | BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10 and modulates cisplatin resistance. | 26655271 |
Type | IDs |
---|---|
Synonymous | EST182763, MRP7, SIMRP7 |
Gene |
UniProtKB-ID:
MRP7_HUMAN,
A0A024RD21_HUMAN
UniprotKB:
Q5T3U5,
A0A024RD21
UniParc:
UPI000004A062,
UPI000013CB7E
EMBL:
AK024446,
AY032599,
AL359813,
AL133613,
CH471081,
AK000002
Ensembl:
ENSG00000124574
KO:
hsa:89845
|
Nucleutide sequences |
EMBL-CDS:
AAK39642.1,
CAB63742.1,
BAB15736.1,
BAA92227.1,
EAX04182.1,
EAX04181.1
Gene_ORFName:
hCG_19009
Ensembl_TRS:
ENST00000244533,
ENST00000372530
|
Protein sequencees |
Ensembl_PRO:
ENSP00000361608,
ENSP00000244533
RefSeq:
XP_011513287.1,
XP_016866943.1,
XP_011513276.2,
XP_016866938.1,
XP_016866936.1,
XP_016866939.1,
XP_016866945.1,
NP_001337447.1,
XP_016866944.1,
XP_016866934.1,
NP_001185863.1,
XP_016866940.1,
NP_258261.2,
XP_016866937.1,
XP_016866942.1,
XP_016866935.1,
XP_011513288.1
|
Others |
UniRef100:
UniRef100_Q5T3U5
UniRef90:
UniRef90_Q5T3U5
UniRef50:
UniRef50_Q5T3U5
UniGene:
Hs.55879
CCDS:
CCDS4896.1,
CCDS56430.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员