例如:"NBL1", "4681", "drought"
收藏
89845 ABCC10

89845

ABCC10

ATP binding cassette subfamily C member 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP binding cassette subfamily C member 10

研究结论

Date Results Publications
2019-07-20 12:59:00 In the cancer cell lines, only rs2125739 of ABCC10 gene was significantly associated with docetaxel cytotoxicity, and this was confirmed in the genome-edited cell line. In the non-small cell lung cancer (NSCLC) patients, there were no significant differences related to rs2125739 genotype in terms of response rate, progression free and overall survival. However, this SNP was associated with grade 3/4 neutropenia. 30890141
2018-03-03 11:25:00 FOXM1 promotes 5-FU resistance by up-regulating ABCC10 expression in colorectal tumor cells. 28051999
2017-08-12 12:07:00 It is thus inferred, that ABCC10 expression in CWR22Rv1 cells is not S phase-specific but is primarily associated with cell proliferation. 28612064
2017-06-10 11:02:00 The present study shows that the protein expression of ABCC10 significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients 27468921
2016-05-21 11:35:00 BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10 and modulates cisplatin resistance. 26655271

名称对应

Type IDs
Synonymous EST182763, MRP7, SIMRP7
Gene
UniProtKB-ID: MRP7_HUMAN, A0A024RD21_HUMAN
UniprotKB: Q5T3U5, A0A024RD21
UniParc: UPI000004A062, UPI000013CB7E
EMBL: AK024446, AY032599, AL359813, AL133613, CH471081, AK000002
Ensembl: ENSG00000124574
KO: hsa:89845
Nucleutide sequences
EMBL-CDS: AAK39642.1, CAB63742.1, BAB15736.1, BAA92227.1, EAX04182.1, EAX04181.1
Gene_ORFName: hCG_19009
Ensembl_TRS: ENST00000244533, ENST00000372530
Protein sequencees
Ensembl_PRO: ENSP00000361608, ENSP00000244533
RefSeq: XP_011513287.1, XP_016866943.1, XP_011513276.2, XP_016866938.1, XP_016866936.1, XP_016866939.1, XP_016866945.1, NP_001337447.1, XP_016866944.1, XP_016866934.1, NP_001185863.1, XP_016866940.1, NP_258261.2, XP_016866937.1, XP_016866942.1, XP_016866935.1, XP_011513288.1
Others
UniRef100: UniRef100_Q5T3U5
UniRef90: UniRef90_Q5T3U5
UniRef50: UniRef50_Q5T3U5
UniGene: Hs.55879
CCDS: CCDS4896.1, CCDS56430.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员