| Type | Description |
|---|---|
| Definition | patched 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:09:00 | The Shh/Ptch1 pathway plays an essential role in the model of VD. | 30306574 |
| 2019-11-16 13:22:00 | Study provide evidence that spatiotemporal expression of Shh, Ptch1, and Gli1 was imbalanced during development of the lumbosacral spinal cord in rat embryos with ethylenethiourea induced anorectal malformations (ARMs). This imbalance may contribute to maldevelopment of the lumbosacral spinal cord and provide a molecular explanation for the complications observed in patients with ARMs. | 30502245 |
| 2019-05-04 11:49:00 | our results highlight miR-369-5p mediated DNMT3A epigenetic silencing of Patched1 as a mechanism of fibroblast proliferation in cardiac fibrosis | 30114436 |
| 2018-08-18 11:40:00 | in adjuvant arthritis fibroblast-like synoviocytes, MeCP2 mediates hypermethylation of PTCH1 gene and decreases the expression of PTCH1 protein, thus activating Hedgehog signaling pathway and increasing secretion of IL-6 and TNF-alpha. | 28573530 |
| 2018-07-21 11:27:00 | Activation of the Hh signaling pathway by silencing PTC1 and PTC2 may reduce inflammation and may ultimately promote spinal cord injury recovery | 29244790 |
| Type | IDs |
|---|---|
| Synonymous | Ptch, Ptch2 |
| Gene |
UniProtKB-ID:
Q6UY90_RAT
UniprotKB:
Q6UY90
UniParc:
UPI00001C057E
EMBL:
AC134760,
AY357891,
AABR07072531,
AABR07026785
Ensembl:
ENSRNOG00000019354
KO:
rno:89830
|
| Nucleutide sequences |
EMBL-CDS:
AAQ67738.1
Ensembl_TRS:
ENSRNOT00000026287
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000026287
RefSeq:
NP_446018.1,
NP_001376185.1
|
| Others |
UniRef100:
UniRef100_Q6UY90
UniRef90:
UniRef90_Q13635
UniRef50:
UniRef50_Q13635
UniGene:
Rn.102312
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员