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89817 Sh2b1

89817

Sh2b1

SH2B adaptor protein 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition SH2B adaptor protein 1

研究结论

Date Results Publications
2019-03-23 10:16:00 miR-14 2-3 p not only mitigate cardiac hypertrophy by directly inhibit the expression of gene SH2B1, but also can protect mitochondrial function in cardiac hypertrophy of vitro and vivo. 30372837
2018-10-27 10:52:00 SH2B1 overexpression resulted in increased viability, reduced lactate dehydrogenase release and a reduction in the expression levels of proteins associated with the apoptotic cascade in PC12 cells under the oxygenglucose deprivation condition. 30015896
2015-05-23 12:30:00 These findings suggest that SH2B1-IRSp53 complexes promote the formation of filopodia, neurite initiation, and neuronal branching. 25586189
2014-07-12 11:00:00 findings demonstrate that SH2B1beta promotes BDNF-induced neurite outgrowth through enhancing pathways involved MEK-ERK1/2 and PI3K-AKT. 24260264
2012-05-26 11:31:00 Long-Evans rats maintained on chow or a high-fat diet (HFD) for 6 weeks. From a total of 19 genes analyzed, seven genes (ETV5, FTO, GNPDA2, KCTD15, TMEM18, MC4R, and SH2B1) were down-regulated in the hypothalamus of HFD compared to chow-fed rats 21779089

名称对应

Type IDs
Synonymous Sh2-b, Sh2b, Sh2bpsm1
Gene
UniProtKB-ID: SH2B1_RAT, M0R617_RAT
UniprotKB: Q62985, M0R617
UniParc: UPI00000E69BE, UPI000166305B, UPI0000E0DB31
EMBL: AABR07005776, U57391, CH473956, AF047577
Ensembl: ENSRNOG00000049181
KO: rno:89817
Nucleutide sequences
EMBL-CDS: AAC04575.1, AAC52601.1, EDM17458.1, EDM17460.1, EDM17464.1
Gene_ORFName: rCG_40223
Ensembl_TRS: ENSRNOT00000074274, ENSRNOT00000071241
Protein sequencees
Ensembl_PRO: ENSRNOP00000066048, ENSRNOP00000064854
RefSeq: NP_001041645.1, XP_006230414.1, NP_604451.2, XP_006230415.1, XP_006230417.1, XP_006230416.1, XP_006230413.1
Others
UniRef100: UniRef100_Q62985, UniRef100_M0R617
UniRef90: UniRef90_Q62985
UniRef50: UniRef50_Q62985
UniGene: Rn.11069

全选

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