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89813 Pdk4

89813

Pdk4

pyruvate dehydrogenase kinase 4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition pyruvate dehydrogenase kinase 4

研究结论

Date Results Publications
2020-05-30 12:56:00 HIF-1a/PDK4/autophagy pathway protects against advanced glycation end-products induced vascular smooth muscle cell calcification. 31376939
2019-11-09 11:00:00 this study suggests that advanced glycation end products accelerate vascular calcification partly through the HIF-1a/PDK4 pathway and suppress glucose metabolism. 30213959
2017-12-30 12:15:00 adipocyte PDK4 gene is a new target of the vitamin A derived retinoic acid and might participate to the reduced fatty acid efflux from the adipocyte 27981737
2016-08-13 11:55:00 PDK2/4 induction and the subsequent lactate surge induce the metabolic shift in the diabetic dorsal root ganglion thereby contributing to the pathogenesis of painful diabetic neuropathy. 26769971
2013-09-07 10:37:00 Chronic dichloroacetate inhibits FOXO1-induced PDK4 upregulation and restores GO, leading to improved bioenergetics and RV function in RVH. 23247844

名称对应

Type IDs
Gene
UniProtKB-ID: PDK4_RAT
UniprotKB: O54937
UniParc: UPI00001314C6
EMBL: AF034577
KO: rno:89813
Nucleutide sequences
EMBL-CDS: AAC00177.1
Protein sequencees
RefSeq: NP_446003.2
Others
UniRef100: UniRef100_O54937
UniRef90: UniRef90_Q16654
UniRef50: UniRef50_Q16654
UniGene: Rn.11766

全选

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研究热度

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