| Type | Description |
|---|---|
| Definition | neuron navigator 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:47:00 | Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis. | 32141789 |
| 2015-04-04 11:27:00 | The +TIP Navigator 1 (NAV1) is important for neurite outgrowth and interacts and colocalizes with TRIO, a Rho guanine nucleotide exchange factor that enables neurite outgrowth by activating the Rho GTPases Rac1 and RhoG. | 25065758 |
| 2014-08-11 10:50:00 | NAV1 forms a complex with the RhoGEF TRIO and the +TIP EB1 on the plus ends of growing microtubules, and regulates TRIO-mediated Rac1 activation and neurite outgrowth. | 25065758 |
| 2010-01-21 00:00:00 | cloning of the gene neuron navigator-1 (NAV1), a human homolog of unc-53, a gene involved in axon guidance in Caenorhabditis elegans | 12079279 |
| Type | IDs |
|---|---|
| Synonymous | POMFIL3, STEERIN1, UNC53H1 |
| Gene |
UniProtKB-ID:
NAV1_HUMAN
UniprotKB:
Q8NEY1
UniParc:
UPI00004562D4,
UPI000150AF0E,
UPI0000470252,
UPI000150AF0C,
UPI000150AF0D,
UPI000016783B,
UPI000150AF0F
EMBL:
AJ251973,
AB032977,
AL512788,
AK022622,
AY043013,
AC092800,
AK022631,
AC096677,
AL645504,
AB033039,
AK024265,
AJ488101,
BC007523
Ensembl:
ENSG00000134369
KO:
hsa:89796
|
| Nucleutide sequences |
EMBL-CDS:
AAH07523.1,
CAD32470.1,
BAB14136.1,
BAB14865.1,
CAB66088.1,
BAB14142.1,
AAL05591.1,
BAA86465.3,
BAA86527.1
Ensembl_TRS:
ENST00000367296,
ENST00000367295
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356265,
ENSP00000356264
RefSeq:
NP_001161210.1,
NP_065176.3
|
| Others |
UniRef100:
UniRef100_Q8NEY1
UniRef90:
UniRef90_Q8NEY1
UniRef50:
UniRef50_Q8NEY1
UniGene:
Hs.585374
CCDS:
CCDS53456.1,
CCDS1414.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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