| Type | Description |
|---|---|
| Definition | solute carrier family 22 member 7 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-20 11:12:00 | the findings revealed the important role of OAT2 in renal secretion and possible reabsorption of creatinine and suggested a molecular basis for potential species difference in the transporter handling of creatinine | 25904762 |
| 2015-10-31 11:04:00 | strongly decreased expression of Oat2 and other transporters in female diabetic ZSF1 rats could possibly impair renal drug excretion, for example, of furosemide | 25710042 |
| 2011-07-23 11:08:00 | Expression of rat OAT2 in HEK (human embryonic kidney)-293 cells stimulates accumulation of the zwitterion trigonelline; subsequently, orotic acid is identified as an excellent and specific substrate of OAT2 from rat. | 21446918 |
| 2010-01-21 00:00:00 | Oat2 mRNA expression was also highest in kidney rather than in liver. Considerably higher Oat2 levels were seen in female kidney as compared with male. | 11907168 |
| 2010-01-21 00:00:00 | induction of Oatp2 expression in liver of fasted mice may be caused by activation of the cAMP-dependent signaling pathway, with the CRE site (-1808/-1804) and CREB being the cis- and trans-acting factors mediating the induction, respectively | 17244698 |
| Type | IDs |
|---|---|
| Synonymous | Oat2 |
| Gene |
UniProtKB-ID:
S22A7_RAT
UniprotKB:
Q5RLM2
UniParc:
UPI00001581C2
EMBL:
AY816233,
L27651
Ensembl:
ENSRNOG00000018420
KO:
rno:89776
|
| Nucleutide sequences |
EMBL-CDS:
AAV66454.1,
AAA57157.1
Ensembl_TRS:
ENSRNOT00000025094
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000025094
RefSeq:
NP_445989.2
|
| Others |
UniRef100:
UniRef100_Q5RLM2
UniRef90:
UniRef90_Q5RLM2
UniRef50:
UniRef50_Q9Y694
UniGene:
Rn.10009
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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