| Type | Description |
|---|---|
| Definition | WASP like actin nucleation promoting factor |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | TRPV4 activates the Cdc42/N-wasp pathway to promote glioblastoma invasion by altering cellular protrusions. | 32843668 |
| 2020-10-24 14:12:00 | The Chlamydia trachomatis secreted effector TmeA hijacks the actin remodeling axis to facilitate cellular invasion. | 32946535 |
| 2020-05-09 10:37:00 | Together, these data support a model wherein TNK2, WASL, and NCK1 comprise a pathway important for the entry of multiple picornaviruses. | 31769754 |
| 2019-10-26 11:41:00 | N-WASP has an early tumour suppressive role in APC-induced intestinal carcinogenesis. | 29672847 |
| 2017-12-30 12:21:00 | N-WASP positively regulates demarcation membrane system development and proplatelet formation, and the Src family kinases in association with CDC42 regulate proplatelet formation through N-WASP | 27685868 |
| Type | IDs |
|---|---|
| Synonymous | N-WASP, NWASP, WASPB |
| Gene |
UniProtKB-ID:
WASL_HUMAN
UniprotKB:
O00401
UniParc:
UPI000013C821
EMBL:
BC052955,
AM295156,
AC006333,
D88460
Ensembl:
ENSG00000106299
KO:
hsa:8976
|
| Nucleutide sequences |
EMBL-CDS:
AAQ96857.1,
AAH52955.1,
BAA20128.1,
CAL26602.1
Ensembl_TRS:
ENST00000223023
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000223023
RefSeq:
NP_003932.3
|
| Others |
UniRef100:
UniRef100_O00401
UniRef90:
UniRef90_O00401
UniRef50:
UniRef50_O00401
UniGene:
Hs.143728,
Hs.731519
CCDS:
CCDS34743.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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