| Type | Description |
|---|---|
| Definition | cholinergic receptor nicotinic alpha 6 subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 11:51:00 | This study is the first showing that CHRNB3/A6 are highly associated with nicotine dependence in a large Chinese Han sample. | 28851948 |
| 2017-11-18 10:13:00 | To gain a better understanding of the pathological processes underlying ND and ND-related behaviors and to promote the development of effective smoking cessation therapies, we here present the most recent studies concerning the genetic effects of the CHRNB3-CHRNA6 gene cluster in ND. | 27327258 |
| 2017-05-13 14:25:00 | More low frequency variants in the CHRNA6/CHRNB3 gene region were observed in cases compared to controls. | 27085880 |
| 2016-03-28 09:41:00 | Chrna6 has a cellular expression signature for retinal ganglion cells with high correlation to Thy1, a known marker. Immunofluorescence confirms this gene is preferentially expressed by RGCs in the young and adult mouse retina and expression is reduced in glaucoma. | 23002780 |
| 2015-12-05 10:10:00 | Data show efficient expression of (alpha6beta2)2beta3 nicotinic acetylcholine receptors (AChRs) in Xenopus oocytes using free subunits with only small changes in alpha6 subunits, while not altering AChR pharmacology or channel structure. | 25068303 |
| Type | IDs |
|---|---|
| Synonymous | CHNRA6 |
| Gene |
UniProtKB-ID:
ACHA6_HUMAN
UniprotKB:
Q15825
UniParc:
UPI0000061DF6,
UPI000018D536
EMBL:
AC087533,
BC014456,
U62435,
AK313521,
Y16282,
AB079251,
AK298798,
CH471080
Ensembl:
ENSG00000147434
KO:
hsa:8973
|
| Nucleutide sequences |
EMBL-CDS:
BAG60933.1,
EAW63207.1,
AAH14456.1,
BAG36301.1,
BAC06855.1,
CAA76155.1,
AAB40113.1
Ensembl_TRS:
ENST00000534622,
ENST00000276410
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000433871,
ENSP00000276410
RefSeq:
NP_004189.1,
NP_001186208.1
|
| Others |
UniRef100:
UniRef100_Q15825
UniRef90:
UniRef90_Q15825
UniRef50:
UniRef50_Q15825
UniGene:
Hs.103128
CCDS:
CCDS56536.1,
CCDS6135.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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