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8945 BTRC

8945

BTRC

beta-transducin repeat containing E3 ubiquitin protein ligase

protein-coding

Homo sapiens

基因描述

Type Description
Definition beta-transducin repeat containing E3 ubiquitin protein ligase

研究结论

Date Results Publications
2021-03-27 14:42:00 The circular RNA FAM169A functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR-583 and BTRC. 32366862
2020-09-05 13:57:00 Bergenin impedes the generation of extracellular matrix in glomerular mesangial cells and ameliorates diabetic nephropathy in mice by inhibiting oxidative stress via the mTOR/beta-TrcP/Nrf2 pathway. 31494242
2019-12-21 12:11:00 CHK1 contains a beta-TrCP recognizable degron domain, which is phosphorylated by AMPK in response to glucose deprivation. 30428154
2019-10-26 10:25:00 Study findings identify beta-TrCP as an important negative regulator for upstream signaling of IkappaBalpha in lipopolysaccharide pathway, and therefore renew the understanding of the roles of beta-TrCP in regulating toll-like receptors inflammatory signaling. 30619291
2019-06-29 10:37:00 Beta transducin repeat-containing protein (beta-TrCP1) interacts with PERIOD2 (PER2) through conserved phosphoswitches i.e. SEP480 and SEP484 residues. 29856966

名称对应

Type IDs
Synonymous BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
Gene
UniProtKB-ID: FBW1A_HUMAN, B2R8L3_HUMAN, B7Z3H4_HUMAN, Q68DS0_HUMAN, A0A0S2Z4P6_HUMAN
UniprotKB: Q9Y297, B2R8L3, B7Z3H4, Q68DS0, A0A0S2Z4P6
UniParc: UPI0000EE3B40, UPI000002AA00, UPI000175052C, UPI000041A0B1, UPI00000012B5
EMBL: AF101784, KU178454, AK313353, AL445463, AK295870, BC027994, GU727631, AL133387, CH471066, AF129530, KU178451, Y14153, AL627424, AK313417, CR749295
Ensembl: ENSG00000166167
KO: hsa:8945
Nucleutide sequences
EMBL-CDS: AAF04464.1, CAA74572.1, AAD08702.1, EAW49774.1, AAH27994.1, EAW49772.1, ADU87633.1, BAG36155.1, BAG36210.1, BAH12210.1, ALQ33912.1, EAW49771.1, CAH18150.1, ALQ33909.1
Gene_ORFName: hCG_1811016
Ensembl_TRS: ENST00000408038, ENST00000370187, ENST00000393441
Protein sequencees
Ensembl_PRO: ENSP00000385339, ENSP00000359206, ENSP00000377088
RefSeq: XP_016872361.1, XP_016872359.1, XP_016872362.1, XP_016872363.1, XP_024304014.1, XP_011538622.1, XP_006718117.1, NP_001243785.1, NP_003930.1, NP_378663.1, XP_024304015.1, XP_016872360.1
Others
UniRef100: UniRef100_Q9Y297, UniRef100_B2R8L3, UniRef100_B7Z3H4
UniRef90: UniRef90_Q3ULA2-2, UniRef90_Q9Y297
UniRef50: UniRef50_Q9Y297
UniGene: Hs.643802
CCDS: CCDS7511.1, CCDS7512.1

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