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8940 TOP3B

8940

TOP3B

DNA topoisomerase III beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition DNA topoisomerase III beta

研究结论

Date Results Publications
2021-01-02 12:49:00 Further evidence of GABRA4 and TOP3B as autism susceptibility genes. 32028044
2020-10-31 13:17:00 Topoisomerase III-beta is required for efficient replication of positive-sense RNA viruses. 32735900
2020-06-06 12:18:00 Our data show that TOP3B is necessary to prevent the accumulation of excessive R-loops and identify TOP3B as a putative cancer gene, and support recent data showing that R-loops are involved in cancer aetiology. 31795919
2019-07-27 12:15:00 Findings indicate the regulation of DNA topoisomerase III beta (TOP3B) activity by post-translational modification (PTM). 29471495
2018-11-03 11:59:00 Structural basis of the interaction between TOP3B and the TDRD3 auxiliary factor has been reported. 28176834

名称对应

Type IDs
Synonymous TOP3B1
Gene
UniProtKB-ID: TOP3B_HUMAN, A0A024R1C2_HUMAN, A8K4N2_HUMAN
UniprotKB: O95985, A0A024R1C2, A8K4N2
UniParc: UPI00015DA66F, UPI000002B59D, UPI00001371A1, UPI000002B59C
EMBL: CR456596, CH471095, AF053082, AF017146, D87012, AK290997, BC002432, AF125216
Ensembl: ENSG00000100038
KO: hsa:8940
Nucleutide sequences
EMBL-CDS: AAH02432.1, AAD29670.1, CAG30482.1, AAD01614.1, BAA20009.1, AAD15791.1, EAW59490.1, EAW59488.1, EAW59487.1, EAW59491.1, BAF83686.1
Gene_ORFName: hCG_2010987
Ensembl_TRS: ENST00000398793, ENST00000357179
Protein sequencees
Ensembl_PRO: ENSP00000349705, ENSP00000381773
RefSeq: NP_001336779.1, NP_001269041.1, NP_003926.1, NP_001336774.1, NP_001336777.1, NP_001336776.1, NP_001269042.1, NP_001336781.1, NP_001336780.1
Others
UniRef100: UniRef100_A8K4N2, UniRef100_O95985
UniRef90: UniRef90_O95985
UniRef50: UniRef50_O95985
UniGene: Hs.436401
CCDS: CCDS13797.1

全选

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