| Type | Description |
|---|---|
| Definition | src kinase associated phosphoprotein 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-07-02 11:22:00 | Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs. | 26577701 |
| 2016-02-19 09:51:00 | Skap2 is necessary for macrophage migration, chemotaxis, global actin reorganization and local actin reorganization upon integrin engagement. | 22976304 |
| 2015-10-03 10:44:00 | SKAP2 expression levels in NSCLC tissues could be a powerful biomarker of poor prognosis. Therefore, SKAP2 is a promising candidate molecular target for Non-small cell lung cancer treatment. | 25862907 |
| 2013-03-30 12:13:00 | results suggest that SKAP2 negatively regulates cell migration and tumor invasion in fibroblasts and glioblastoma cells by suppressing actin assembly induced by the WAVE2-cortactin complex | 23161539 |
| 2011-10-29 10:21:00 | analysis of substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate | 21719704 |
| Type | IDs |
|---|---|
| Synonymous | PRAP, RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R |
| Gene |
UniProtKB-ID:
SKAP2_HUMAN,
B7Z5R3_HUMAN
UniprotKB:
O75563,
B7Z5R3
UniParc:
UPI0000073C8C,
UPI0000EE4473
EMBL:
AK222885,
BC002893,
AK299317,
AF072166,
CH471073,
AJ004886,
AK313209,
AF051323,
CH236948,
BC036044,
AC003999,
AB014486,
AC011299
Ensembl:
ENSG00000005020
KO:
hsa:8935
|
| Nucleutide sequences |
EMBL-CDS:
AAH36044.1,
CAA06193.1,
AAC39924.1,
BAA36194.1,
EAL24231.1,
AAC99296.1,
EAW93859.1,
AAS02033.1,
AAS07536.1,
AAH02893.1,
BAD96605.1,
BAG36025.1,
BAH12999.1,
EAW93860.1
Gene_ORFName:
hCG_38391
Ensembl_TRS:
ENST00000345317
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000005587
RefSeq:
NP_001290397.1,
NP_003921.2,
XP_016868260.1
|
| Others |
UniRef100:
UniRef100_O75563
UniRef90:
UniRef90_O75563
UniRef50:
UniRef50_O75563
UniGene:
Hs.200770,
Hs.610137
CCDS:
CCDS5400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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