| Type | Description |
|---|---|
| Definition | HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:52:00 | Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2. | 31665549 |
| 2020-11-21 13:12:00 | HERC2 regulates RPA2 by mediating ATR-induced Ser33 phosphorylation and ubiquitin-dependent degradation. | 31582797 |
| 2020-10-31 13:17:00 | Prognostic impact of HERC2 protein and pink-eyed dilution protein in uveal melanoma. | 32686068 |
| 2020-09-12 16:00:00 | NudC-like protein 2 restrains centriole amplification by stabilizing HERC2. | 31427565 |
| 2020-02-22 11:17:00 | analysis of the HERC2-associated proteome revealed striking differential protein expression between neurodevelopmental disorder cases and controls | 30902390 |
| Type | IDs |
|---|---|
| Synonymous | D15F37S1, MRT38, SHEP1, jdf2, p528 |
| Gene |
UniProtKB-ID:
HERC2_HUMAN,
A8KAQ8_HUMAN
UniprotKB:
O95714,
A8KAQ8
UniParc:
UPI00015DAB75,
UPI00004578F7
EMBL:
AF225409,
AF224245,
AF224249,
AF225408,
AF224247,
AF224253,
AF225404,
AF224257,
AC135329,
AF225401,
AF225403,
AF225407,
AF224256,
AF224243,
AF224250,
AC091304,
AF224244,
AF225402,
AF224255,
AF224252,
AF224254,
AF225400,
AF224242,
AC126332,
AF225406,
AF224248,
AF225405,
AF224251,
BC148318,
AF224246,
AF071172
Ensembl:
ENSG00000128731
KO:
hsa:8924
|
| Nucleutide sequences |
EMBL-CDS:
AAO27478.1,
AAO27484.1,
AAO27474.1,
AAO27482.1,
AAO27479.1,
AAO27476.1,
AAO27473.1,
AAO27477.1,
AAO27483.1,
AAO27481.1,
AAO27480.1,
AAD08657.1,
AAO27475.1,
AAI48319.1
Ensembl_TRS:
ENST00000261609
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261609
RefSeq:
XP_016878185.1,
XP_006720789.1,
XP_016878184.1,
XP_016878186.1,
XP_005268333.1,
NP_004658.3,
XP_016878187.1,
XP_006720790.1
|
| Others |
UniRef100:
UniRef100_O95714,
UniRef100_A8KAQ8
UniRef90:
UniRef90_A8KAQ8,
UniRef90_O95714
UniRef50:
UniRef50_A8KAQ8,
UniRef50_O95714
UniGene:
Hs.434890,
Hs.610412,
Hs.741019
CCDS:
CCDS10021.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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