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892 CCNC

892

CCNC

cyclin C

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin C

研究结论

Date Results Publications
2019-06-29 11:52:00 cyclin C binding stimulates the reduction of low-GTPase activity Drp1 oligomers into dimers capable of producing high-GTPase activity filaments. 30516433
2019-04-13 11:26:00 Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. 29440396
2016-02-27 11:28:00 our results suggest that mTORC1 activation in NAFLD and insulin resistance results in down-regulation of the CDK8-CycC complex and elevation of lipogenic protein expression. 26042770
2015-12-05 10:49:00 results suggest that CCNC temporarily protects SRC-2 against degradation and this event is involved in the transcriptional regulation of SRC-2 cell cycle target genes. 25986860
2015-05-16 11:43:00 Cancer-mediated CDK8 point mutations (D173A and D189N) change the binding pattern of cdk8 to its partner, CycC. 24754906

名称对应

Type IDs
Synonymous CycC, SRB11, hSRB11
Gene
UniProtKB-ID: CCNC_HUMAN, Q7Z4L3_HUMAN
UniprotKB: P24863, Q7Z4L3
UniParc: UPI00004EC068, UPI0000169CFB
EMBL: U40738, U40734, AK298558, BC041123, U40733, U40730, U40736, BC056153, U40737, U40732, U40728, U40735, CH471051, U40729, AB125137, BC010135, U40731, AL137784, M74091, U40739
Ensembl: ENSG00000112237
KO: hsa:892
Nucleutide sequences
EMBL-CDS: BAG60753.1, AAC50825.1, EAW48466.1, AAH56153.1, EAW48465.1, AAH41123.1, AAH10135.1, BAD00144.1
Gene_ORFName: hCG_1757197
Ensembl_TRS: ENST00000523985, ENST00000520429, ENST00000523799
Protein sequencees
Ensembl_PRO: ENSP00000430014, ENSP00000430119, ENSP00000428982
RefSeq: NP_001013417.1, XP_011534534.1, XP_016866925.1, NP_001350466.1, NP_005181.2
Others
UniRef100: UniRef100_P24863
UniRef90: UniRef90_P24863
UniRef50: UniRef50_P24863
UniGene: Hs.430646, Hs.633351
CCDS: CCDS47461.1, CCDS34502.1

全选

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