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8907 AP1M1

8907

AP1M1

adaptor related protein complex 1 subunit mu 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition adaptor related protein complex 1 subunit mu 1

研究结论

Date Results Publications
2019-03-09 10:44:00 It has been shown that the cytoplasmic domains of furin bind the mu subunits of AP-1 and AP-2 in a phosphorylation-dependent manner. 30135209
2019-01-19 10:09:00 Here, the authors demonstrate that dileucine motifs in the hepatitis C virus NS2 protein mediate AP-1A, AP-1B, and AP-4 binding and cell-free virus release. Moreover, they reveal that AP-4, an adaptor not previously implicated in viral infections, mediates cell-to-cell spread and hepatitis C virus trafficking. 29535204
2018-07-28 11:19:00 found 31 ORF9p interaction partners, among which was AP1M1, the mu subunit of the adaptor protein complex 1 (AP-1). AP-1 is a heterotetramer involved in intracellular vesicle-mediated transport and regulates the shuttling of cargo proteins between endosomes and the trans-Golgi network via clathrin-coated vesicles. 29793951
2017-10-07 11:16:00 Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. The basic patch on micro1 that interacts with the Nef acidic cluster also contributes to the binding of endogenous acidic cluster proteins. 28743825
2015-02-14 12:17:00 CNNM4 is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B 25449265

名称对应

Type IDs
Synonymous AP47, CLAPM2, CLTNM, MU-1A
Gene
UniProtKB-ID: AP1M1_HUMAN, A0A024R7K8_HUMAN, B3KNH5_HUMAN, Q59EK3_HUMAN
UniprotKB: Q9BXS5, A0A024R7K8, B3KNH5, Q59EK3
UniParc: UPI0000124FEA, UPI00004F6E3E, UPI000051DDEE, UPI000015F31C
EMBL: AB209808, AF290613, DQ059565, AK027528, AC020911, CH471106, BC017469
Ensembl: ENSG00000072958
KO: hsa:8907
Nucleutide sequences
EMBL-CDS: AAH17469.1, AAY54246.1, AAK28024.1, EAW84540.1, EAW84539.1, BAG51337.1, BAD93045.1
Gene_ORFName: hCG_36931
Ensembl_TRS: ENST00000291439, ENST00000444449
Protein sequencees
Ensembl_PRO: ENSP00000388996, ENSP00000291439
RefSeq: NP_115882.1, NP_001123996.1
Others
UniRef100: UniRef100_Q9BXS5, UniRef100_B3KNH5, UniRef100_Q59EK3
UniRef90: UniRef90_Q9BXS5, UniRef90_A0A2I3SE57
UniRef50: UniRef50_Q9BXS5
UniGene: Hs.71040
CCDS: CCDS46008.1, CCDS12342.1

全选

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