| Type | Description |
|---|---|
| Definition | copine 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:50:00 | High CPNE1 expression is associated with tumorigenesis and radioresistance via the AKT singling pathway in triple-negative breast cancer. | 32181526 |
| 2019-05-11 10:15:00 | We observed that knockdown of CPNE1 and increased expression of miR-335-5p inhibits cell proliferation and motility in NSCLC cells, and found that CPNE1 was a target of miR-335-5p. | 29970127 |
| 2019-03-09 10:59:00 | Study find that CPNE1 expression is upregulated in non-small cell lung cancer (NSCLC) and associated with advanced TNM stage, lymph node and distant metastasis. Furthermore, its knockdown inhibits the cell cycle in NSCLC cells. These data strongly suggest that CPNE1 is an oncogene in NSCLC and serves an important role in tumorigenesis of NSCLC progression. | 30221693 |
| 2018-09-08 11:56:00 | Results demonstrated that CPNE1 was highly expressed in the osteosarcoma (OS) tissues and cell lines. Its knockdown significantly inhibited cell proliferation, colony formation, invasion and metastasis in OS cell lines. | 29207139 |
| 2018-07-14 10:04:00 | CPNE1 overexpression can upregulate TRAF2 expression in prostate cancer DU-145 cells as determined by Western blotting and immunofluorescence assays. | 29151113 |
| Type | IDs |
|---|---|
| Synonymous | COPN1, CPN1 |
| Gene |
UniProtKB-ID:
CPNE1_HUMAN,
B0QZ18_HUMAN
UniprotKB:
Q99829,
B0QZ18
UniParc:
UPI0000049386,
UPI0000D4B36B
EMBL:
AF314092,
CH471077,
CR456790,
U83246,
AL109827,
BC001142
Ensembl:
ENSG00000214078
KO:
hsa:8904
|
| Nucleutide sequences |
EMBL-CDS:
EAW76187.1,
AAH01142.1,
EAW76178.1,
EAW76186.1,
EAW76177.1,
EAW76185.1,
EAW76190.1,
EAW76189.1,
AAC15920.1,
EAW76175.1,
EAW76173.1,
CAG33071.1,
EAW76179.1,
AAG49297.1,
EAW76174.1,
EAW76183.1,
EAW76176.1
Gene_ORFName:
hCG_38213
Ensembl_TRS:
ENST00000352393,
ENST00000397443,
ENST00000317677
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380585,
ENSP00000336945,
ENSP00000317257
RefSeq:
NP_690903.1,
NP_690902.1,
NP_003906.2,
NP_690905.1,
NP_690904.1,
NP_001185792.1
|
| Others |
UniRef100:
UniRef100_Q99829
UniRef90:
UniRef90_Q99829
UniRef50:
UniRef50_Q99829
UniGene:
Hs.246413,
Hs.700188
CCDS:
CCDS13260.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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