| Type | Description |
|---|---|
| Definition | myotubularin related protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | Exosomal miR-1910-3p promotes proliferation, metastasis, and autophagy of breast cancer cells by targeting MTMR3 and activating the NF-kappaB signaling pathway. | 32531321 |
| 2021-01-09 13:25:00 | Three SNPs of FCRL3 and one SNP of MTMR3 are associated with immunoglobulin A nephropathy risk. | 31780315 |
| 2020-10-24 13:55:00 | Association of MTMR3 rs12537 at miR-181a binding site with rheumatoid arthritis and systemic lupus erythematosus risk in Egyptian patients. | 31444373 |
| 2020-02-29 12:11:00 | Study demonstrated that high levels of MTMR3 were associated with relapsefree survival and the triplenegative breast cancer subtype, as well as with a protumorigenic function in human breast cancer cells. Its knockdown suppressed proliferation and colony formation through cell cycle arrest and autophagy in MDAMB231 cells. These results provided novel insights into the pathological mechanism of breast cancer. | 31485632 |
| 2016-08-13 10:49:00 | Data suggest MTMR3 has multiple functions in regulation of autophagy; one mechanism appears to be direct interaction between MTMR3 and mTORC1 (MTOR, mLST8, raptor) which inhibits phosphorylation activity of mTORC1; MTMR3 is localized to Golgi apparatus. | 26787466 |
| Type | IDs |
|---|---|
| Synonymous | FYVE-DSP1, ZFYVE10 |
| Gene |
UniProtKB-ID:
MTMR3_HUMAN,
A0A024R1I2_HUMAN
UniprotKB:
Q13615,
A0A024R1I2
UniParc:
UPI0000073EF2,
UPI000006EF30,
UPI0000072406
EMBL:
CR456525,
BC152455,
BC142713,
CH471095,
AC003071,
U58034,
AF233436,
AF233437,
BC148216,
AF233438,
AB002369
Ensembl:
ENSG00000100330
KO:
hsa:8897
|
| Nucleutide sequences |
EMBL-CDS:
AAF40204.1,
AAI52456.1,
CAG30411.1,
AAC79119.1,
AAI42714.1,
EAW59852.1,
BAA20826.2,
EAW59855.1,
AAI48217.1,
AAF40205.1,
AAF40203.2,
AAB83949.1,
EAW59853.1
Gene_ORFName:
hCG_41636
Ensembl_TRS:
ENST00000333027,
ENST00000351488,
ENST00000401950,
ENST00000406629
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384077,
ENSP00000331649,
ENSP00000384651,
ENSP00000307271
RefSeq:
NP_694690.1,
NP_694691.1,
NP_066576.1
|
| Others |
UniRef100:
UniRef100_Q13615,
UniRef100_A0A024R1I2
UniRef90:
UniRef90_Q13615
UniRef50:
UniRef50_Q13615
UniGene:
Hs.474536
CCDS:
CCDS46682.1,
CCDS13871.1,
CCDS13870.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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