| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2B subunit delta |
| Date | Results | Publications |
|---|---|---|
| 2016-07-02 10:56:00 | A novel missense mutation within EIF2B4 is associated with vanishing white matter disease. | 25600065 |
| 2015-07-25 10:57:00 | demonstrate that DAP5 associates with eIF2beta and eIF4AI to stimulate IRES-dependent translation of cellular mRNAs | 25779044 |
| 2014-04-19 12:17:00 | The functional effects of selected vanishing white matter disease mutations in EIF2B2-5 by coexpressing mutated and wild-type subunits in human cells. | 21560189 |
| 2012-12-22 10:46:00 | analysis of developmental splicing deregulation in leukodystrophies related to EIF2B mutations | 22737209 |
| 2012-09-29 10:07:00 | A mutation .626G>A [p.Arg209Gln] in exon 7 and c.1399C>T [p.Arg467Trp] in exon 13 of the EIF2B4-Gens. | 21503715 |
| Type | IDs |
|---|---|
| Synonymous | EIF-2B, EIF2B, EIF2Bdelta |
| Gene |
UniProtKB-ID:
EI2BD_HUMAN,
Q9HBP7_HUMAN,
F8W8L6_HUMAN,
B4DUP5_HUMAN,
Q71US4_HUMAN,
E7ERK9_HUMAN
UniprotKB:
Q9UI10,
Q9HBP7,
F8W8L6,
B4DUP5,
Q71US4,
E7ERK9
UniParc:
UPI00017A7F61,
UPI000173A54F,
UPI0000366EE5,
UPI000002A88A,
UPI0000129AB2,
UPI0000208145,
UPI00002317D0,
UPI0000073026
EMBL:
BC001870,
AF112207,
AF218009,
CH471053,
AC074117,
BC091502,
AJ011306,
AJ011305,
AJ011307,
AK300734,
AF057699,
AJ011308,
JQ991007
Ensembl:
ENSG00000115211
KO:
hsa:8890
|
| Nucleutide sequences |
EMBL-CDS:
EAX00591.1,
AAY14843.1,
AAF17195.1,
AAH01870.1,
CAB57261.1,
AAH91502.1,
CAB57305.1,
CAB57260.1,
CAB57304.1,
AAG17251.1,
AFM43698.1,
BAG62407.1,
AAQ13438.1
Ensembl_TRS:
ENST00000451130,
ENST00000347454,
ENST00000445933,
ENST00000405940,
ENST00000493344
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394397,
ENSP00000394869,
ENSP00000233552,
ENSP00000384375,
ENSP00000429323
RefSeq:
NP_001305894.1,
NP_001305897.1,
NP_001305898.1,
XP_011531449.1,
XP_006712195.1,
NP_001029288.1,
NP_751945.2,
NP_001305896.1,
NP_001305895.1,
NP_056451.3
|
| Others |
UniRef100:
UniRef100_Q9UI10,
UniRef100_B4DUP5,
UniRef100_Q9HBP7,
UniRef100_E7ERK9,
UniRef100_Q71US4,
UniRef100_F8W8L6
UniRef90:
UniRef90_Q9UI10,
UniRef90_B4DUP5,
UniRef90_F8W8L6,
UniRef90_A0A087WW69,
UniRef90_Q9UI10-2
UniRef50:
UniRef50_Q9UI10,
UniRef50_F8W8L6,
UniRef50_B4DUP5
UniGene:
Hs.169474
CCDS:
CCDS46245.1,
CCDS33164.1,
CCDS46244.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员