| Type | Description |
|---|---|
| Definition | sphingosine-1-phosphate lyase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:23:00 | Heterogenous Nuclear Ribonucleoprotein H1 Promotes Colorectal Cancer Progression through the Stabilization of mRNA of Sphingosine-1-Phosphate Lyase 1. | 32630435 |
| 2020-02-29 10:48:00 | SGPL1 Deficiency is associated with Primary Adrenal Insufficiency. | 30517686 |
| 2019-02-16 10:26:00 | High SGPL1 expression is associated with Huntington's disease. | 28706199 |
| 2018-09-01 10:04:00 | describe the sequential expression and localization of the endogenous S1P regulators SGPP-1 and SGPL-1 and highlight their contribution to the sphingolipid rheostat in inflammation. | 29375197 |
| 2018-03-31 11:12:00 | Data show that sphingosine kinase 1 (SPHK1) was significantly upregulated in oral squamous cell carcinoma (OSCC) tissues and low levels of sphingosine-1-phosphate lyase 1 (SGPL1) mRNA correlated with a worse overall survival, and that sphingosine-1-phosphate receptor 2 (S1PR2) is over-expressed in a subset of tumours, which in part mediates sphingosine 1-phosphate (S1P)-induced migration of OSCC cells. | 27160553 |
| Type | IDs |
|---|---|
| Synonymous | NPHS14, S1PL, SPL |
| Gene |
UniProtKB-ID:
SGPL1_HUMAN
UniprotKB:
O95470
UniParc:
UPI0000032F1A
EMBL:
BC052991,
CH471083,
AJ011304,
AK314615,
AB033078,
AF144638
Ensembl:
ENSG00000166224
KO:
hsa:8879
|
| Nucleutide sequences |
EMBL-CDS:
AAD44755.1,
AAH52991.1,
EAW54414.1,
BAA86566.1,
CAA09590.2,
BAG37181.1
Ensembl_TRS:
ENST00000373202
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362298
RefSeq:
XP_006718116.1,
XP_011538620.1,
XP_011538618.1,
NP_003892.2,
XP_005270320.1,
XP_011538619.1
|
| Others |
UniRef100:
UniRef100_O95470
UniRef90:
UniRef90_O95470
UniRef50:
UniRef50_O95470
UniGene:
Hs.499984
CCDS:
CCDS31216.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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