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8874 ARHGEF7

8874

ARHGEF7

Rho guanine nucleotide exchange factor 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho guanine nucleotide exchange factor 7

研究结论

Date Results Publications
2021-01-02 12:50:00 ARHGEF7 (beta-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function. 32188698
2020-11-28 13:12:00 Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex. 31754215
2020-04-18 11:20:00 our results demonstrate the importance of AMPK-mediated phosphorylation of beta1Pix at Ser(71), which promotes 14-3-3 interactions with beta1Pix and Nedd4-2 to form a tripartite ENaC inhibitory complex, in the mechanism of ENaC regulation by AMPK 31566435
2019-03-30 12:59:00 Expression of ARHGEF7 is significantly increased and associated with metastasis in colorectal adenocarcinoma. 30132516
2019-03-02 10:17:00 Induced association of beta-PIX with GIT1 is essential for the stimulation of intestinal epithelial restitution by activating Rac1, and this signaling pathway is tightly regulated by cellular polyamines. 29191942

名称对应

Type IDs
Synonymous BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB
Gene
UniProtKB-ID: ARHG7_HUMAN, A0A024RDY9_HUMAN, Q5W9H1_HUMAN, E9PDQ5_HUMAN, B7Z6G2_HUMAN, B7Z344_HUMAN
UniprotKB: Q14155, A0A024RDY9, Q5W9H1, E9PDQ5, B7Z6G2, B7Z344
UniParc: UPI0001B790C4, UPI00002132CC, UPI0001914D40, UPI0000167BA5, UPI000045239F, UPI0000131B52, UPI000013FF99, UPI000178DE45, UPI0001914EFD, UPI00003BF70E
EMBL: AB177848, BC050521, BC033905, AL390754, AB177849, AK300272, CH471085, BC060776, AL834228, AB075521, D63476, AK295472, AL139086, AL353704
Ensembl: ENSG00000102606
KO: hsa:8874
Nucleutide sequences
EMBL-CDS: AAH60776.1, AAH33905.1, AAH50521.1, CAD38906.1, BAD66827.1, BAA09763.2, EAX09143.1, BAE45764.1, EAX09144.1, EAX09149.1, BAD66826.1, BAH13248.1, BAH12080.1
Gene_ORFName: Nbla10314, hCG_1811466
Ensembl_TRS: ENST00000426073, ENST00000375741, ENST00000375723, ENST00000317133, ENST00000375739, ENST00000375736, ENST00000478679
Protein sequencees
Ensembl_PRO: ENSP00000364875, ENSP00000325994, ENSP00000364891, ENSP00000397068, ENSP00000364888, ENSP00000364893, ENSP00000417596
RefSeq: NP_001106985.1, XP_006720019.1, NP_001340979.1, NP_001340978.1, NP_001340977.1, XP_016876305.1, NP_663788.1, NP_001317526.1, NP_001340975.1, NP_003890.1, NP_001340988.1, NP_001340986.1, NP_001340985.1, NP_001317527.1, NP_001340981.1, NP_001307782.1, XP_016876308.1, XP_011519435.1, NP_001307783.1, XP_016876312.1, XP_016876318.1, XP_024305196.1, NP_001307781.1, NP_001106984.1, XP_016876303.1, NP_001106983.1, NP_001340983.1, XP_016876304.1, XP_016876311.1, NP_001340982.1, NP_001307780.1, NP_001340984.1, NP_001340990.1, XP_016876317.1, NP_001340989.1, NP_001340980.1, NP_001340987.1, NP_001340976.1, XP_016876309.1, XP_016876310.1
Others
UniRef100: UniRef100_B7Z6G2, UniRef100_Q5W9H1, UniRef100_Q14155, UniRef100_E9PDQ5, UniRef100_A0A024RDY9, UniRef100_B7Z344
UniRef90: UniRef90_B7Z6G2, UniRef90_Q14155, UniRef90_E9PDQ5, UniRef90_Q5W9H1
UniRef50: UniRef50_A0A2K5XCS3, UniRef50_Q14155, UniRef50_A0A250Y3N7, UniRef50_G3QX74
UniGene: Hs.508738
CCDS: CCDS45068.1, CCDS45069.1, CCDS9521.1, CCDS32009.1, CCDS86362.1

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