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887 CCKBR

887

CCKBR

cholecystokinin B receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition cholecystokinin B receptor

研究结论

Date Results Publications
2019-02-02 11:41:00 we found that all eight neuroendocrine neoplasm expressed CCKBR and neuroendocrine markers in a majority of tumor cells. The same markers were also expressed in a proportion of adenocarcinomas supporting the view that gastrin is important in the development of gastric cancer 28980157
2018-11-03 10:19:00 We concluded that low serum gastrin is related to increased risk of ER(+) BC development. The results also established that CCKBR/ERK/P65 signaling function is generally tumor suppressive in ER(+) BC, indicating therapies should focus on restoring, not inhibiting, CCKBR/ERK/P65 pathway activity. 30115027
2018-01-06 12:48:00 High CCK2R expression is associated with cancer. 26910279
2017-08-12 11:10:00 These results suggest that Z-360 exerts an anti-tumor effect through a reduction in anti-apoptosis factors by blocking CCK2R 28739697
2017-07-29 11:19:00 High CCK-BR expression is associated with Gastric Cancer. 27518872

名称对应

Type IDs
Synonymous CCK-B, CCK2R, GASR
Gene
UniProtKB-ID: GASR_HUMAN, E9PIC8_HUMAN
UniprotKB: P32239, E9PIC8
UniParc: UPI0000157524, UPI0000000C18, UPI0000DFF6ED, UPI00001F9C05
EMBL: L07746, AC022762, L10822, AF441129, AH006311, L04473, S70057, D21219, AY029770, AC068733, BC000740, AF239668, D13305, AK292064, BT006789, L08112, AY322551
Ensembl: ENSG00000110148
KO: hsa:887
Nucleutide sequences
EMBL-CDS: AAC27510.1, AAH00740.1, BAF84753.1, AAA35660.1, AAB30766.2, AAN32829.1, AAC37528.1, AAA91831.1, BAA02564.1, AAP84364.1, AAA35657.1, AAK38351.1, AAF67174.1, BAA04759.2, AAP35435.1
Ensembl_TRS: ENST00000525462, ENST00000334619, ENST00000532715
Protein sequencees
Ensembl_PRO: ENSP00000335544, ENSP00000435534, ENSP00000432079
RefSeq: NP_795344.1, XP_016874005.1, NP_001304958.1, NP_001350481.1
Others
UniRef100: UniRef100_E9PIC8, UniRef100_P32239
UniRef90: UniRef90_P32239, UniRef90_A0A096NAQ2
UniRef50: UniRef50_P30553, UniRef50_A0A096NAQ2
UniGene: Hs.203
CCDS: CCDS86175.1, CCDS7761.1

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